Bacterial microcompartments (BMCs) are proteinaceous organelles contained within prokaryotes used to facilitate reactions with increased efficiency, or to carry out reactions with intermediates that are harmful to the cell if released into the cytoplasm. Oftentimes, compartments are used to metabolize unique carbon sources, such as 1,2-propanediol (1,2-PD), whose metabolic pathway...
The basal layer of human epidermis is composed of progenitor cells that both self-renew and differentiate to form stratified epidermal tissue; this process requires strict, dynamic regulation of gene expression. The Super Elongation Complex (SEC) regulates gene expression at the level of transcription elongation by releasing RNA Polymerase II from...
In the past few years, educators have been pushing for an integration of the arts into science, technology, engineering, and math (STEM) learning in order to promote innovation and creativity in these fields. The present study explores the relation between creativity and STEM learning among young children in digital and...
On college campuses, one in five women will experience sexual assault in some capacity over the course of their undergraduate experience. College men in fraternities are three times more likely to commit sexually assaultive acts than non-Greek students. Despite pervasive knowledge that fraternity members are often involved in rape on...
The theorists who developed Social Justice Education (SJE) claim that its goals are: to critically analyze how oppression operates on an individual, cultural, and institutional level, to harness empathy and respect for others, and, ultimately, to commit to working for lasting change. However, the literature lacks research on how to...
This study reports on the results of a psychosocial questionnaire survey of professional symphonic musicians in the United States. The response rate was 12.36% (n= 395) and the sample was members of the International Conference of Symphonic and Opera Musicians (ICSOM) which is a conglomerate of the top 50 orchestras...
Situated in the heart of urban Taipei, the capital of Taiwan, Chiang Kai-shek Memorial Hall (1976) stands as a monument to the eponymous first president of the Republic of China (ROC). Consisting of a main memorial hall, opera theater, Western concert hall, and surrounding gardens, the memorial complex was constructed...
The decision to breastfeed or formula feed is a largely contested one by mothers, healthcare administrators, and politicians. Yet, research suggests that both breastfeeding and formula feeding are healthy ways to provide nourishment to newborn babies. Considering this, I sought to analyze why this decision is such a site of...
The study of local adaptation in plants is critical for understanding the evolution of traits that contribute to survival in a dynamic environment, the genes underlying them, and the general process of adaptation. However, in the study of natural, non-model plant species, population-level whole-genome sampling is not always feasible and...
Type 2 diabetes (T2D) affects over 422 million people worldwide. Within their multi-payer healthcare system, Germany has used standardized, evidence-based interventions called Disease Management Programs (“DMP”s) to manage T2D since 2002. Studies have shown markedly improved health care delivery and health outcomes, including reduced incidence of diabetic secondary complications, decreasing...
The study of local adaptation in plants is critical for understanding the evolution of traits that contribute to survival in a dynamic environment, the genes underlying them, and the general process of adaptation. However, in the study of natural, non-model plant species, population-level whole-genome sampling is not always feasible and...
Research has found that both schizophrenia populations and populations at clinical high risk for psychosis show alterations in facial affect expressivity, specifically blunting. However, it is unknown whether these alterations occur prior to onset, or whether they develop as a consequence of psychosis onset processes. The current study sought to...
Artificial agent development is motivated by the dream of making machines perform undesirable labor instead of humans. To replace humans in undesirable labor, it follows that the machines should not engage in actions that will lead to devastating consequences. They should be “moral” artificial agents. In my paper, I deal...
"The goal of our research has been to create software that extends the benefits of virtual reality
(VR) to mathematics education. We report on the design and evaluation of a VR application meant
to support students’ reasoning about objects in three-dimensional (3D) coordinate systems and to
explore the possibilities of...
In humans, posttraumatic stress disorder (PTSD) is co-morbid with major depressive disorder. Individuals who are exposed to stress prior to a traumatic event have an increased likelihood of developing PTSD. To study this increased vulnerability, a rat model was developed using the Stress Enhanced Fear Learning (SEFL) paradigm. This study...
According to the principle of free fall, only gravity acts upon an object in midair. However, as with all scientific principles, free fall plays out differently in practice. In my experiment, I first tested to see the effect of changing the glycerol weight-percentage of a drop of glycerol-water on its...
This project is comprised of primary source research on the field of semiconductor microscopy. We were interested in determining a more interdisciplinary application of this technology, as the most frequently cited applications are for defense purposes such as drug screening or infrared imaging. When we researched, we found that these...
The Modern Orthodox Jewish (MO) community currently functions on the fantasy that MO teens are receiving all their messaging around sex from their Jewish schools and communities. The messaging these students receive tells them to refrain from sex and touching people of the opposite sex until marriage. This messaging can...
Image colorization is the process of artificially coloring a black and white image such that this fabrication appears realistic and authentic to the viewer. There are many nontrivial applications of this process, such as the colorization and augmentation of historical photos as well as the removal of color tone filters...
Children come to understand race within a historically-established racial hierarchy, but they have the agency to accommodate or resist this establishment as they form their own racial identities. Previous research identified distinct narrative types that either reinforce existing societal structures (Master Narratives) or disrupt them (Alternative Narratives). The Counternarrative...
Much has already been discovered about the Hedgehog (Hh) signaling pathway and its involvement in patterning and tissue development in embryos, but the specific functions its key components play has not yet been fully elucidated. One potential component is the protein kinase Dop, which is involved in cellular trafficking. Here,...
Past research suggests that stereotypes about collective identities (i.e. race, ethnicity, and gender) shape aspirations. However, less is known about how actual representation of collective identity relates to aspirations. The proportion of an identity in a given career will be used as an indicator of numeric representation and I hypothesize...
This project was originally motivated by a lifelong love of the Harry Potter series and a teenage love for fan fiction and other fancreated works. I was motivated to do research when I stumbled upon the lack of inclusivity in many fan communities, which I found to be shocking. In...
Women in developing countries occupy a unique role in the economy that is often underappreciated, informal and highly vital to the country’s economic stability. Despite their high productivity and output, women in countries such as Morocco lack support from their government and communities as well as the infrastructure necessary to...
There are few concerns greater than those of a parent with an adult with an intellectual or developmental disability (I/DD). How is she or he going to be taken care of as she or he ages? The government provides services and support in the pursuit of care and services, but...
When navigating through space, the brain must integrate sensory information with past experiences to choose behaviors that are most likely to produce a positive outcome. Striatal medium spiny neurons (MSNs) expressing dopamine receptor 1 (D1) and dopamine receptor 2 (D2) receive sensory and motor information from cortical and midbrain regions...
It has been hypothesized that mindfulness-based programs with a primary focus on teaching self-compassion or empathy will have greater effects on self-compassion and empathy than will mindfulness-based exposure programs, which focus primarily on enhancing present moment awareness and reducing distress. However, because research on mindfulness-based exposure programs has centered on...
Over the last decades, there have been many changes in the business world that are associated with 52 percent of Fortune 500 companies either going bankrupt, being acquired by other companies, or ceasing to exist. One critical change is the transformation of the economy into a knowledge-based economy, where information...
In the Marvel Comics series Moon Knight, a mercenary believes an ancient Egyptian deity has brought him back from the dead so he can become the eponymous superhero. However, the mercenary’s symptoms of schizophrenia suggest he is instead simply suffering from a psychological break. From 1975-1999, Moon Knight stories used...
The goal of this research paper is to analyze concepts of armed conflict and peacebuilding from a gender perspective using a feminist epistemology approach.
I examine the impact of armed conflict on women, and the implications of women’s roles in armed conflict and in peacebuilding processes post-conflict. In doing so,...
Negative emotional behaviors, such as criticism, defensiveness, contempt, and stonewalling, that spouses may show during conflict are key predictors of marital dissatisfaction. Existing research has focused on middle-class couples, but little is known about how these negative emotional behaviors predict marital satisfaction among couples from socioeconomically diverse backgrounds. The present...
Standard narratives on the relationship between art and urban development detail art networks as complicit agents in processes of upscaling and gentrification connected to the political and economic elite. My thesis challenges the conventional narrative by investigating the relationship between grassroots art spaces, tied to local, community- based interests, and...
Patients with psychosis experience deficits in multisensory integration (MSI), or the communication between different sensory modalities, such as sound and sight. One way to assess multisensory integrations is by utilizing voice-pitch tasks in which participants hear the pitch of their own voice artificially altered by a computer. When healthy individuals...
Previous research has shown that bodily gesture aids in learning words and is useful for musical expression. However, no studies to date have examined the use of gesture in learning words and music together. The original impetus for the present study was observing students with cognitive disabilities learn musical songs,...
With a large sphere of activity and ability to transfer data through wireless communication system, drones have proven to be more and more useful in both research and manufacturing. Whether by allowing researchers to collect measurements or filmmakers to attain aerial shots, the use of drone has allowed collection of...
In indoor environments, bacteria face selective pressure to carry antibiotic resistant genes (ARGs) from antimicrobial substances used in furniture, building materials, and personal care products. Humans rely on antibiotics to clear bacterial infections, so understanding the way in which these genes are transferred, i.e., on mobile genetic elements, is critical....
This study aims to advance our basic understanding of how we perceive objects in our environment. It’s unclear whether we understand object structure based on only how we perceive or on how it truly exists in the world. Examining eye-movements provides insight into how our visual system represents and understands...
Due to their ability to be engineered for specific cellular targeting, nanoparticles (NPs) have emerged as promising drug delivery vessels for immunotherapeutic and vaccination treatments. However, a major unsolved obstacle for cell-specific nanoparticle delivery is non-specific circulatory clearance by the mononuclear-phagocytic system(MPS). Comprised of various phagocytic cells, the MPS removes...
The bacterial CRISPR/Cas9 system shows promise as a genome-editing tool to treat human disease. It is integral to understand the binding and unbinding kinetics of Cas9 to its target DNA to study specificity of the Cas9 protein. Standard practices involve the use of negatively charged polymer Heparin to reduce unspecific...
Given any polyhedron in R3, we can cut it open along its edges, flatten it out, and obtain a polygon in the plane R2. In this project, we explored the opposite process, an open question that was first posed about 70 years ago: given a polygon in R2, what is...
Anxiety disorders are the most common group of mental illnesses in the United States and affect over 15% of the population. Prior work utilizing electroencephalogram (EEG) to investigate event-related potentials (ERPs) from the scalp has shown success in isolating certain neural correlates related to increased risk for developing anxiety disorders....
Posttraumatic stress disorder (PTSD) is an anxiety disorder characterized by flashbacks of the traumatic event and high comorbidity with major depressive disorder (MDD). Prior stress is known to increase the likelihood of developing PTSD after experiencing a traumatic event. Currently, PTSD is diagnosed clinically, its biological etiology is not known...
Expanding on research done on the mental health and happiness benefits associated with romantic relationships, this study investigates whether identity denial, the experience of being socially denied one’s chosen identity by having others refuse to acknowledge that identity, presents a challenge for bisexual people within committed romantic relationships. For straight,...
Physiological linkage (i.e., the covariation of moment-to-moment physiology between individuals) is thought to play an important role in relationship functioning. The present study examined physiological linkage across interbeat interval (IBI) and skin conductance levels (SCL) in a sample of married spouses (N=106) during both a pleasant and a conflict conversation...
Skeletal sexual dimorphism presents itself in humans primarily through the anatomical shape of the cranium and pelvis. However, some physical anthropologists maintain that climate could have an effect on human sexual dimorphism. Despite ongoing research pertaining to climatic effects on soft tissue or size dimorphism, little to no research has...
A survey of adults (n = 706) found low levels of awareness of two social movements aimed at decreasing weight stigma: the Fat Acceptance Movement and Health at Every Size movement. For HAES, providing a brief story of an overweight person who endorses HAES improved perceptions of the movement.