Northwestern University

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Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics

Description:

The ability of a cell to regulate its mechanical properties is central to its function. Emerging evidence suggests that interactions between the cell nucleus and cytoskeleton influence cell mechanics through poorly understood mechanisms. Here we conduct quantitative confocal imaging to show that loss of A-type lamins tends to increase nuclear...

Keyword:

Nuclear lamins, LINC complex, Cell mechanics, and Cytoskeleton

Creator:

Amir Vahabikashi, Suganya Sivagurunathan, and Fiona Ann Sadsad Nicdao

Owner:

Amir Vahabikashi

Publisher:

Northwestern University

Language:

English

Date Uploaded:

04/03/2022

Date Modified:

04/03/2022

Date Created:

04.02.2022

Resource Type:

Dataset