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-
- Description:
- As our world is increasingly filled with data visualizations, having the skills to leverage data visualizations is essential for participation in society. Confident engagement with data visualizations is critical for being an educated member of society; however, research has shown that it is difficult for individuals to digest and gain...
- Subject:
- Design, Educational technology, and Computer science
- Creator:
- Thompson, JaCoya
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_971103 and http://dissertations.umi.com/northwestern:16451
-
- Description:
- Prior studies about restatements generally examine outcomes under assumed auditor responsibility. Surprisingly, however, about 20% of the restatements obtained from Audit Analytics correspond to cases where the current auditor was not engaged during the misstatement period. I refer to these cases as uninvolved. The first chapter examines current literature findings...
- Keyword:
- misstatement announcements, audit outcomes to restatement, market reaction to restatement, audit firm independence, and audit firm reputation
- Subject:
- Accounting
- Creator:
- Gomez, Pedro Enrique
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14607 and etdadmin_upload_661490
-
- Description:
- Decision making is an essential and indispensable element in everyday life. It is posited that parallel, distinct systems subserving deliberative, goal-directed control and automatic, habitual control underlie decision making. Computational accounts suggest that model-based and model-free learning strategies give rise to these two systems respectively. The model-based system is a...
- Keyword:
- Reward, fMRI, and Decision making
- Subject:
- Neurosciences
- Creator:
- Zhong, Wanting
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14552 and etdadmin_upload_647965
-
- Description:
- This dissertation investigates two ways in which personality psychology should move beyond the traditional approach of measuring personality with broad domains composed of trait descriptors, as exemplified by the Big Five taxonomy. The first study (Chapter 2) suggests an alternative to the traditional approach of aggregating personality items into domains....
- Keyword:
- Statistical learning, Behavioral frequency, Behavior, Nuance, Personality, and BISCUIT
- Subject:
- Psychology
- Creator:
- Elleman, Lorien Grey
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15260 and etdadmin_upload_764195
-
- Description:
- Motivated by rhythms in the brain, we investigate the synchronization of noisy and all-to-all pulse-coupled oscillators. We consider a case where the oscillatory excursions are of varying amplitude and where only sufficiently large excursions result in the output pulses that drive the interactions between the oscillators. In the regime of...
- Keyword:
- Oscillators, Markov Renewal, Events, Mixed-mode, Spiking, and Noise
- Subject:
- Applied mathematics
- Creator:
- Karamchandani, Avinash Jagdish
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16397 and etdadmin_upload_959050
-
- Description:
- For years, neuroscientists have strived to understand memory consolidation, where salient memories are sorted and organized into distributed cortical networks for long-term storage. A large body of sleep research suggests that slow-wave sleep is an optimal opportunity for memory consolidation, and that consolidation is driven, at least in part, by...
- Keyword:
- olfactory reactivation, functional MRI, slow-wave sleep, ventromedial prefrontal cortex, memory replay, and memory consolidation
- Subject:
- Neurosciences
- Creator:
- Shanahan, Laura Kathleen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14493 and etdadmin_upload_634332
-
- Description:
- Leptin, a peptide mainly secreted in proportion to adipose tissue mass, increases energy expenditure with a parallel increase in breathing. The existence of a leptin-mediated neural circuit linking breathing to metabolism has been speculated, yet the precise central mechanisms were unknown. In my thesis, I show that optogenetic activation of...
- Keyword:
- NALCN, obesity, and Nucleus of the Solitary Tract
- Subject:
- Neurosciences
- Creator:
- Do, Jeehaeh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_763656 and http://dissertations.umi.com/northwestern:15246
-
- Description:
- Every day, we communicate through computers on projects ranging from a group lunch order to booking a flight to learning critical medical information. And every day, we also miscommunicate through computers: We don’t pick up on an intentionally humorous response, or we miss the criticality of a request. This is...
- Keyword:
- Social Science, Computer-Mediated Communication, Human-Computer Interaction, Cognitive Science, and Keystroke Dynamics
- Subject:
- Communication
- Creator:
- Goodkind, Adam Nathaniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 03/24/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_962518 and http://dissertations.umi.com/northwestern:16417
-
- Description:
- This dissertation aims to understand the contribution of schools to reducing bullying behaviors and, in turn, to examine the benefits for students of attending a school that effectively reduces bullying. In doing so, this dissertation contributes to the literature on bullying by a) locating the school as a key environment...
- Keyword:
- Bullying
- Subject:
- Education policy and Secondary education
- Creator:
- Kiguel, Sebastian
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_986319 and http://dissertations.umi.com/northwestern:16588
-
- Description:
- This thesis deals with modeling long-term deformation and failure of concrete and shale structures. First concrete structures are studied. For concrete structures, design lifetime of over a hundred years is required. Shrinkage, swelling, creep and Alkali-silica reaction are significant parts of the long-term deformation of concrete and are studied here....
- Keyword:
- Alkali-Silica Reaction, Creep and Shrinkage, Branching of Hydraulic Cracks, Microprestress, Creep of Shale, and Cement Hydration
- Subject:
- Geophysics, Computational physics, and Civil engineering
- Creator:
- RAHIMI-AGHDAM, SAEED
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14537 and etdadmin_upload_640235
-
- Description:
- Reproduction requires a complex orchestration of processes from the formation of the reproductive system through the successful development of the fetus, and nutrients are necessary to fuel these processes during many aspects of reproduction. Zinc is an essential metal that is fundamental in gamete maturation, gonadogenesis, and fertilization. Disruption in...
- Keyword:
- Ovulation, Labile zinc, Caenorhabditis elegans, Zinc transporters, Reproductive biology, and Live imaging
- Subject:
- Molecular biology, Genetics, and Cellular biology
- Creator:
- Sue, Aaron Christopher
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_902758 and http://dissertations.umi.com/northwestern:16074
-
- Description:
- Muscle strength assessment is a standard part of any clinical evaluation. Due to the kinematic and muscular redundancy in the human musculoskeletal system, muscle strength can not be measured directly in vivo. Clinicians utilize specific postures and forces to bias the muscles of interest, then infer the muscle strength from...
- Keyword:
- Active Learning , Parameter Estimation , Musculoskeletal Model, and Cervical Spine
- Subject:
- Mechanical engineering and Biomechanics
- Creator:
- Abbott, Rebecca Elizabeth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_797807 and http://dissertations.umi.com/northwestern:15487
-
- Description:
- Anthropologists engaging with biopolitical theory have commonly assumed that biomedicine is a tool for enacting state-based policies to manage population health. Recent insights in medical anthropology have troubled this assumption, calling into question the role of physicians as “handmaidens” of state-based health policy. I use my position as a physician-anthropologist...
- Keyword:
- anthropology of reproduction, pregnancy, opioid use disorder, illicit substance use disorders, biopolitics, and medical anthropology
- Subject:
- Cultural anthropology
- Creator:
- Premkumar, Ashish
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_965675 and http://dissertations.umi.com/northwestern:16433
-
- Description:
- Electrical spinal cord stimulation is an emerging treatment for spinal cord injury that can improve walking and bladder control, among many other functions. While the anatomical location of the motor pools for muscles involved in locomotion in the lumbosacral cord has been identified, the map of the functional output of...
- Subject:
- Neurosciences
- Creator:
- Patterson, Jacqueline
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16163 and etdadmin_upload_917878
-
- Description:
- This dissertation examines three empirical questions related to human capital in developing countries. Chapter 1 studies the educational and labor market impacts of the telesecundarias, Mexican secondary schools that use televisions to deliver instruction. In areas where there is an insufficient supply of qualified teachers, delivering instruction through technology may...
- Keyword:
- Development, Human Capital, and Economics
- Subject:
- Economics
- Creator:
- Navarro-Sola, Laia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15075 and etdadmin_upload_741177
-
- Description:
- Complex fluids are ubiquitous, from natural materials to manufactured products. Understanding their behavior under flow is vital for engineering these materials. Extensional flow, despite being industrially relevant and often producing dominant impacts upon complex fluids, is an underserved topic compared to shear flow due to a lack of reliable apparatuses...
- Keyword:
- cross-slot flow, carbon nanotube suspension, wormlike micelle, x-ray scattering, planar extensional flow, and lamellar surfactant
- Subject:
- Chemical engineering
- Creator:
- Luo, Binbin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_624324 and http://dissertations.umi.com/northwestern:14431
-
- Description:
- Thermoelectric materials are of particular interest in a variety of fields because of their ability to directly convert heat to electricity (and vice versa), however, they struggle to gain widespread adoption because of their low efficiency. A common strategy in the field of thermoelectricity is to introduce material defects into...
- Keyword:
- Mesoscale, Doping, Thermoelectric, EBSD, Electron Microscopy, and Semiconductor
- Subject:
- Materials Science and Energy
- Creator:
- Grovogui, Jann Albert
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15371 and etdadmin_upload_779059
-
- Description:
- We consider the statistical study of partially observed queueing systems arising in application areas such as hospital networks, data centers and cloud computing systems. Since these services operate under strict performance requirements, a statistical understanding of their performance is of great practical interest. A key challenge in these settings is...
- Subject:
- Operations research
- Creator:
- Proskynitopoulos, Alexej
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15419 and etdadmin_upload_781003
-
- Description:
- Molecules and materials featuring unpaired electrons are fundamental elements of modern energy, device, and imaging technologies. The high sensitivity of electronic spins to their surroundings renders these compounds further attractive as environmental sensors. In order to successfully realize these applications, the electronic spins must be precisely controlled. One promising strategy...
- Keyword:
- bioresponsive probes, transition metal compounds, metal-organic magnets, electronic spin, and magnetic resonance imaging
- Subject:
- Inorganic chemistry
- Creator:
- Thorarinsdottir, Agnes Eva E
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/28/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_705667 and http://dissertations.umi.com/northwestern:14946
-
- Description:
- Understanding the characteristics of interfaces between materials and solvent media such as structure, chemistry, and charge remains crucial to determining the properties and performance of numerous systems and technologies. This thesis focuses specifically on characterizing the interactions of water at oxide interfaces. A large collection of questions remains unanswered about...
- Subject:
- Chemistry
- Creator:
- Ma, Emily
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_968387 and http://dissertations.umi.com/northwestern:16438
-
- Description:
- To better prepare for earthquakes, we need to know how large they will be, how strong the shaking will be, and how often they will occur. To answer these questions, seismologists look to past earthquakes to better understand future hazards. Earthquakes, however, are complex physical phenomena that occur on timescales...
- Keyword:
- Earthquake statistics, Seismology, and Probability models
- Subject:
- Geophysics
- Creator:
- Neely, James Scott
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_933449 and http://dissertations.umi.com/northwestern:16291
-
- Description:
- This dissertation is about designing learning environments that foreground students’ epistemic agency as they do science in a science classroom. I build on the prior work that combines two important strands in learning sciences - agent-based modeling of complex systems and constructionism to design learning environments. I call such learning...
- Keyword:
- Restructurations, Agent-based models, Constructionism, Computational Thinking, and Scientific inquiry
- Subject:
- Education, Educational technology, and Science education
- Creator:
- Dabholkar, Sugat
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15865 and etdadmin_upload_863334
-
- Description:
- Since the mid-20th century, urbanization has altered the physical landscape and brought social, economic and lifestyle changes to populations worldwide. In the Global South, this has dramatically affected environmental conditions of settlements, communities, and households, with both positive and negative consequences for population health. The objective of this dissertation is...
- Subject:
- Physical anthropology
- Creator:
- McCabe, Kimberly A.
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_934882 and http://dissertations.umi.com/northwestern:16297
-
- Description:
- This dissertation develops a new framework and algorithms for statistical process control of stochastic textured surface data that have no distinct features other than stochastic characteristics that vary randomly (e.g., image data of textiles or material microstructures and surface metrology data of metal parts). All methods are general and nonparametric...
- Keyword:
- Industrial Statistics, Anomaly Detection, Defect Detection, Supervised Learning, Quality Engineering, and Image Dissimilarity
- Subject:
- Industrial engineering
- Creator:
- Bui, Anh Tuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_680004 and http://dissertations.umi.com/northwestern:14772
-
- Description:
- No two cells in a population are identical to each other. Cell populations are almost universally heterogeneous, with their heterogeneity or variability often underlying complex emergent behavior and phenotypes. Heterogeneity presents a challenge to the discovery, characterization, and control of multicellular systems. Heterogeneity exists across multiple scales, ranging from the...
- Keyword:
- Circadian Rhythms, Systems Biology, Control Theory, Dynamical Systems, and Mathematical Modeling
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- Balakrishnan, Narasimhan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_879749 and http://dissertations.umi.com/northwestern:15942
-
- Description:
- The first chapter of the dissertation analyzes a moral hazard problem where a firm incentivizes a team of complementary workers in the presence of trust concerns. As we show, when concerned about team members not trusting each other, the firm typically sacrifices statistically-relevant information, compensating some workers based solely on...
- Subject:
- Economic theory
- Creator:
- Camboni, Matteo
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_900398 and http://dissertations.umi.com/northwestern:16031
-
- Description:
- The microtubule (MT) network and associated regulatory proteins play a critical role during viral infection from facilitating viral particle transport towards the nucleus upon entry to later mediating virion assembly and egress. Many of the precise mechanisms by which viruses commandeer the host MT network to propagate infection remain poorly...
- Keyword:
- TACC3, virus, microtubules, and +TIP
- Subject:
- Virology, Microbiology, and Cellular biology
- Creator:
- Furey, Colleen Patricia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_856328 and http://dissertations.umi.com/northwestern:15823
-
- Description:
- This dissertation offers a novel interpretation of Aristotle’s notion of teaching (didaskalia). In Part I, I defend my claim that we can find in Aristotle’s works a conception of teaching, which is a crucial yet under-explored part of his theory of education. In Part II, I use this interpretation to...
- Keyword:
- Teaching, Education, Aristotle, and Moral Education
- Subject:
- Philosophy
- Creator:
- Cochran, William Bruce McBean
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15114 and etdadmin_upload_743644
-
- Description:
- In the Western Common Law tradition, legal decisions constrain and guide future cases involving the same legal issues. Although the legal academy disagrees about the specific nature of such precedential reasoning, including about the role of analogy in legal reasoning, there is ample evidence from cognitive science that analogical learning...
- Keyword:
- Precedential Reasoning, Rule Learning, Analogy, Legal Reasoning, AI and Law, and Analogical Learning
- Subject:
- Law and Artificial intelligence
- Creator:
- Blass, Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_969522 and http://dissertations.umi.com/northwestern:16441
-
- Description:
- As humans have evolved over time, so have the materials that they rely on. From the Stone Age through the Iron Age, entire eras have been defined by specific materials, their corresponding properties, and the applications they have enabled. This is still true to this day, as the Silicon Age...
- Subject:
- Nanoscience
- Creator:
- Kluender, Edward James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15286 and etdadmin_upload_764959
-
- Description:
- In most markets, consumers of goods and services have vastly more options available to them than they will consider closely. At the point of making a decision, consumers are choosing between only a small subset (i.e., a consideration set) of all possible alternatives. The preceding process that forms these consideration...
- Subject:
- Economics
- Creator:
- Lam, Honn Tai
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16063 and etdadmin_upload_902107
-
- Description:
- Polymer nanocomposites are a class of advanced materials comprised of soft polymer matrix and nano-filler inclusions. While it has been found qualitatively that enhancements of material properties could be achieved by dispersing inorganic nano-particles into organic polymer matrix, the intrinsic governing principles of such composite has not been thoroughly studied...
- Keyword:
- Interphase, Data Mining, Design Optimization, Finite Element Analysis, Deep Learning, and Microstructure Characterization and Reconstruction
- Subject:
- Mechanical engineering, Computer science, and Engineering
- Creator:
- Li, Xiaolin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14436 and etdadmin_upload_625304
-
- Description:
- Solvent-rich polyelectrolyte complexes display a wide range of rheological properties, when different environmental parameters are applied. Due to the low energy barrier of the complexation (~10 kT), these materials possess tunable properties, with the states of these materials varying from Newtonian liquids to very tough hydrogels. This thesis aims to...
- Keyword:
- polyelectrolyte, thermo-thickening, fracture, gels, and viscoelasticity
- Subject:
- Materials Science
- Creator:
- Chen, Yaoyao
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_662844 and http://dissertations.umi.com/northwestern:14666
-
- Description:
- The role of providing care for a loved one with Alzheimer’s disease can expose friends and family caregivers to significant stress over an extended period of time, resulting in a host of negative outcomes like increased depression and anxiety, and diminished quality of life. However, previous studies have found that...
- Keyword:
- psychological well-being, positive emotion, caregiving, online intervention, Alzheimer's disease, and eHealth
- Subject:
- Clinical psychology, Health sciences, and Psychology
- Creator:
- Kwok, Zhenting Ian
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16329 and etdadmin_upload_941336
-
- Description:
- NSD2, a histone methyltransferase specific for methylation of histone 3 lysine 36 (H3K36), exhibits a glutamic acid to lysine mutation at residue 1099 (E1099K) in childhood acute lymphocytic leukemia (ALL). Cells harboring this mutation can become the predominant clone in relapsing disease. We studied the effects of this mutant enzyme...
- Keyword:
- oncology, acute lymphocytic leukemia, histone post-translational modifications, epigenetics, and cancer genetics
- Subject:
- Molecular biology, Oncology, and Cellular biology
- Creator:
- Swaroop, Alok
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14456 and etdadmin_upload_626665
-
- Description:
- Light trapping with standing waves has been achieved using photonic bandgap crystals, metal-dielectric waveguides and periodic metal nanocavity arrays. Compared with photonic materials, plasmonic metal nanocavities can provide light confinement at the sub-wavelength scale with strong near-field electric enhancement. The localized surface plasmons of individual metal nanoparticles can collectively couple...
- Keyword:
- Lattice plasmons, Plasmonics, nanolasing, and Surface lattice resonance
- Subject:
- Nanotechnology, Optics, and Nanoscience
- Creator:
- Li, Ran
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15032 and etdadmin_upload_726683
-
- Description:
- Dysfunction in mitochondrial dynamics is believed to contribute to a host of neurological disorders and has recently been implicated in cancer metastasis. The outer mitochondrial membrane adapter proteins Miro1 and Miro2 play a role in the regulation of mitochondria. Each paralog comprises two GTPase domains flanking two centrally located calcium/magnesium-binding...
- Subject:
- Cellular biology
- Creator:
- Smith, Kyle P
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15631 and etdadmin_upload_831047
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- Description:
- This thesis document is comprised of three research projects. The first investigates the active vibrational modes involved in twisted intramolecular charge transfer in a Julolidine-BODIPY dyad using two-dimensional electronic spectroscopy along with DFT calculations. We identified two types of vibrations, compression and torsional motion, as playing an important role in...
- Subject:
- Organic chemistry, Physical chemistry, and Chemistry
- Creator:
- Fisher, Jeremy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16773 and etdadmin_upload_1014057
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- Description:
- The advancement of nanotechnology is at least partially dependent on the ability to synthesize and arrange complex nanostructures on a substrate. Nanolithography, or the patterning of materials at the sub-micrometer length-scale, has been traditionally performed using a number of methods such as conventional photolithography, ion-beam etching, and electron-beam lithography. While...
- Keyword:
- Scanning Probe, Nanolithography, Lithography, Electrochemical, Polymer, and Hydrogel
- Subject:
- Nanotechnology, Nanoscience, and Materials Science
- Creator:
- Golnabi, Rustin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15442 and etdadmin_upload_791089
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- Description:
- High-throughput methods enable rapid experimentation and/or screening of thousands of samples simultaneously. Mass-spectrometry based methods are of particular interest since they provide a label-free way to detect all species present in a given reaction mixture. To circumvent sample preparation and purification—which is typically a slow process—the Mrksich group developed a...
- Keyword:
- SAMDI, Biochemical Assays, High-Throughput, Single-Cell, and Mass Spectrometry
- Subject:
- Chemistry
- Creator:
- Hakim Moully, Elamar
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15661 and etdadmin_upload_836023
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- Description:
- The social groups to which individuals belong, as well as the identities that result from these group memberships, exert powerful influences on their political attitudes. Additionally, political elites offer cues that shape these same preferences—often by targeting and interacting with identities. However, there remain underexplored pathways by which elites can...
- Keyword:
- political psychology, political elites, political communication, identity, intergroup relations, and political behavior
- Subject:
- Political science
- Creator:
- Rothschild, Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15103 and etdadmin_upload_742932
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- Description:
- Some of the oldest drugs targeting metabolism are the antifolates such as aminopterin and methotrexate (MTX). MTX started being used in the 1950s to treat rheumatoid arthritis. Aminopterin and MTX both target one carbon metabolism and inhibit proliferation of cells. MTX was a potent inhibitor of inflammation, because it prevented...
- Keyword:
- macrophage, LPS, glutathione, metabolism, inflammation, and serine
- Subject:
- Biology
- Creator:
- Rodriguez, Arianne
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_638528 and http://dissertations.umi.com/northwestern:14513
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- Description:
- Connecting structure and function in nanoscale engineered materials and devices relies on the analysis of the fundamental arrangement of matter, frequently under dynamic conditions. The demand to image structures at fundamental length scales has touched inorganic materials, biology, and frequently hybrid hard/soft materials with unique phenomena driven by heterogeneous components....
- Keyword:
- Imaging, Materials Imaging, Soft Materials, Crystallography, Machine Learning, and Electron Microscopy
- Subject:
- Nanoscience, Materials Science, and Computer science
- Creator:
- Hujsak, Karl
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14515 and etdadmin_upload_638887
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- Description:
- Soft functional materials are fundamentally interesting from a chemistry standpoint and have exciting applications in robotics, chemical and biomolecule sensing, and biomedical engineering. In addition, soft materials are also useful in lithography, particularly cantilever-free scanning probe lithography (CFSPL). Because of their low modulus, biocompatibility, stimuli responsiveness, malleability, and other characteristics,...
- Subject:
- Chemistry
- Creator:
- Oh, EunBi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_844916 and http://dissertations.umi.com/northwestern:15750
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- Description:
- In the first two decades of the 21st century, metal organic frameworks (MOFs) have attracted much attention in both fundamental-research and-industrial application areas. Derived from a vast library of both inorganic metal nodes and organic linker bridges, MOFs are crystalline materials whose structures and chemical environments can both be tuned...
- Keyword:
- Catalysis, Hierarchically porous materials, Water treatment, and Metal organic frameworks
- Subject:
- Chemistry
- Creator:
- Zhang, Furui
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_818384 and http://dissertations.umi.com/northwestern:15561
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- Description:
- In a new analysis of Renaissance pastoral that draws on ecocriticism, queer theory, and a historicist approach, this dissertation finds a green and inhuman world that opposes the modern view that humans differ significantly from, and enjoy a right of dominion over, nonhuman species and the environment. Through readings of...
- Keyword:
- Machiavelli, ecocriticism, Shakespeare, nature, posthumanism, and pastoral
- Subject:
- Comparative literature, Italian literature, and English literature
- Creator:
- Pederson, Alicia Sands
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15618 and etdadmin_upload_829081
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- Description:
- Dynamic decision-making is a complex process that relies on our ability to generate, evaluate and implement a variety of strategies. Understanding how people navigate this process is a difficult problem that requires a wide range of methodologies. This study details a combination of behavioral experiments, computational modeling, and neuroimaging that...
- Keyword:
- Memory Systems, Decision Making, Computational Neuroscience, Learning, Cognitive Modeling, and Category Learning
- Subject:
- Cognitive psychology, Psychology, and Neurosciences
- Creator:
- Reuveni, Ben
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15045 and etdadmin_upload_732002
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- Description:
- We broaden the scope of existing dark matter searches at the Large Hadron Collider (LHC) by considering phenomena such as bound state formation and by utilizing simple extensions of well-studied models in the literature. First, we consider the Mono-X studies at the LHC, where the production of dark matter occurs...
- Subject:
- Theoretical physics and Particle physics
- Creator:
- Krovi, Venkat Sai Anirudh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_797580 and http://dissertations.umi.com/northwestern:15481
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- Description:
- “Musical Networks in Bergamo and the Borders of the Venetian Republic, 1580–1630,” examines the mediation and circulation of northern Italian music through social and professional networks with an emphasis on Bergamo, a thriving musical center during this period. In so doing, I challenge established narratives of early modern history that...
- Keyword:
- Early Modern Italy, Sixteenth-Century Music, Seventeenth-Century Music, Giovanni Cavaccio, Bergamo, and Venetian Republic
- Subject:
- History, European history, and Music history
- Creator:
- Rosenholtz-Witt, Jason
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_764519 and http://dissertations.umi.com/northwestern:15270
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- Description:
- This dissertation argues that the convergence of industrialized wage-labor, increased economic precariousness, close and partisan elections, and weak ballot laws dramatically increased the incidence of economic voter intimidation between 1873 and 1896. When this form of coercion primarily affected African American voters, as it did in the 1860s, politicians did...
- Keyword:
- elections, coercion, secret ballot, labor, race, and voter intimidation
- Subject:
- History, American history, and Political science
- Creator:
- Cohn-Postar, Gideon
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15213 and etdadmin_upload_759978