Historians have long argued that humanitarianism—what Thomas Haskell once described as “alleviating the suffering of distant strangers”—first emerged in eighteenth-century Europe as part of a complex set of perceptual changes involving capitalist growth, Enlightenment ideas, and Christian values. Given these claims, it is no coincidence that humanitarianism has often been...
Topology optimization is a powerful tool for maximizing structural performance, enabling multifunctionality of the structure, and reducing the materials waste and cost for sustainable manufacturing. However, current topology optimization tools are limited to a few scales, and the potential of nested topology optimization in engineering design has yet to be...
Early transition metal organometallics chemisorbed on extremely Brønsted acidic sulfated metal oxides such as sulfated alumina (AlS) and sulfated zirconia (ZrS) produce highly active single-site catalysts for olefin polymerization, alkene and arene hydrogenation, and alkane hydrogenolysis, typically with a large percentage of catalytically significant sites. The low support conjugate basicity...
Photochemistry allows chemists to harness the energy in specific wavelengths of light and use it to achieve new chemical transformations. These chemical transformations are often impossible or energetically demanding under traditional thermal conditions. My dissertation focuses broadly on different strategies to apply visible-light photochemistry and photocatalysis to the development of...
Policies supporting families with young children provide an important context for human development. The two primary public policies available to caregivers around and after childbirth are parental leave and early care and education (ECE). A substantial body of research evaluates the effects of parental leave and ECE policies on various...
This dissertation observes interaction to explore the influence of group argument in decision-making in mock juries. The goals of this investigation were to observe two-sided deliberations of a task-oriented decision-making group, map the dichotomous arguments and provide insight into what influences were at play in the final decision. The study...
How molecular chirality manifests at the nano- to macroscale has been a scientific puzzle since Louis Pasteur discovered biochirality. In general, amphiphilic molecules can organize into a variety of assembly shapes including micelles, spherical vesicles, cylindrical micelles, and planar bilayers. However, when such amphiphilic molecules are chiral, helical ribbons, helicoidal...
Heart failure is a growing clinical problem, and inherited cardiomyopathies contribute significantly to heart failure. Among the many genes associated with inherited cardiomyopathies, mutations in FLNC, the gene encoding the cytoskeletal protein filamin C, associate with a range of cardiomyopathy and increased risk for arrhythmia and sudden cardiac death in...
In recent years, motivated by the approaching of quantum limit for classic information science, the development of quantum information science (QIS) has drawn considerable interest from chemists and physicians. Different from classical bits which can only be localized on two different states, quantum bit, which can be simplified as qubit,...
Nilotinib is a highly effective tyrosine kinase inhibitor used to treat Chronic Myeloid Leukemia (CML). While nilotinib successfully treats CML, a common and serious side effect is development of nilotinib-induced arterial disease (NAD) even in patients without pre-existing risk factors. This side effect is not seen with imatinib, a CML...
Mycobacterium tuberculosis (Mtb) infection elicits both protein and lipid antigen-specific T cell responses. However, the incorporation of lipid antigens into subunit vaccine strategies and formulations has been under-explored, and the properties of vaccine-induced Mtb lipid-specific memory T cells have remained elusive. Mycolic acid (MA), a major lipid component of the...
In the late 2000’s, scientific studies in cultural heritage saw a great advancement in macro X-ray fluorescence (XRF) imaging of paintings. These images are used to generate elemental distribution maps, which aid in identifying chemical elements and paint pig- ments as well as their locations throughout the layers of the...
Objective: To evaluate patient-reported experiences of telehealth and disparities in access, use, and satisfaction with telehealth visits during the COVID-19 pandemic (aim 1), to evaluate prevalence of portal use pre-, peri-, and post-pandemic, among the C3 cohort, and investigate any disparities in use by sociodemographic factors (aim 2), and to...
Heterogenous catalysis is the pillar of chemical production and a crucial aspect for optimization toward a sustainable future. To improve the current design of heterogeneous catalysts of maximal activity and product selectivity, gaining fundamental understanding of the catalytic active sites is crucial. The nature of active sites has been the...
In this thesis, I study the effects of spillovers in all-pay auctions and the effects ofregulating wages and hours on the labor market. In the first chapter, I study a model of
asymmetric all-pay auctions with spillovers. In this model, players compete for a prize, and
the sunk effort players...
Air pollution is a pervasive environmental issue that has significant impacts on human health. Urban areas are particularly susceptible to high levels of air pollution due to concentrated emissions and populations. Urban air pollution has been linked to a range of adverse health effects, including respiratory diseases, cardiovascular diseases,...
Biological systems that perform critical reactions like carbon dioxide reduction, water oxidation, or phosphonate ester hydrolysis consist of many separate components with many different degrees of
freedom. While the functionality of pieces of these systems can be replicated synthetically to some
degree, the integration of synthetic catalysts into an overall...
The main topic of this thesis is generation in derived categories of coherent sheaves on smooth projective varieties. We develop a new approach that allows us to give a new proof of a recent result by Olander that powers of an ample line bundle generate the bounded derived category of...
Equilibrium models of star formation successfully derive the globally-averaged Kennicutt-Schmidt (KS) relation, positing that star formation rates (SFRs) are self- regulated by the turbulence in the interstellar medium (ISM) generated by stellar feedback. However, these models make assumptions that may not be achieved in realistic galaxy systems. Cosmological zoom-in simulations,...
An important tenet in memory research is the dissociation between explicit and implicit memory systems in the brain. Whereas a robust literature exists on the consolidation of memories in the explicit domain, research on implicit memory consolidation is relatively understudied, particularly questions about what is being consolidated and the mechanisms...
On March 11, 1966, Indonesian President Soekarno suddenly transferred executive power to the Army, which has played a role in the Indonesian state and society since the late 1950s. This act replaced Soekarno’s own government with a military dictatorship dubbed the New Order, which lasted for nearly 32 years. Why...
As sound changes advance across large geographic areas, they progress unevenly across populations. The speakers who lead these changes often share macro-social identities, like place or social class affiliations (e.g. Nesbitt 2018; Wagner et al. 2016). But the features undergoing these macro-level sound changes also hold social meanings related to...
The negative early and late health consequences from exposure to artificial sources of radiation are particularly apparent in victims of radiological emergencies who were diagnosed with cancer, radiation pneumonitis, among other conditions. The renaissance of nuclear energy, increased use of ionizing radiation in the medical field, and nuclear threats from...
Polymers occupied nearly every facet of our daily lives, and enhancing their mechanical and fracture properties has long been an important topic in the field of polymer science. Based on the various need in applications, polymers are designed to have a range of characteristics such as tackiness, optical properties, mechanical...
We all—users, businesses, governments, and the general public—expect internet platform companies, like Meta, Alphabet, and Amazon to govern their users. Without platform governance, we all experience disasters like foreign election interference, vaccine misinformation, counterfeiting, and even genocide.
Unfortunately, the platform companies have failed. To this day, despite the lessons from...
This project utilizes QCI Inc.’s Qatalyst quantum optimization tools to find the most optimal solution to a randomly generated maze. The maze is traversed and mapped into a spanning tree and then transformed into a set of linear constraint functions. The constraint functions and an objective matrix are used to...
Utilizing a quantum computer and Microsoft Q# SDK to create a quantum neural network aimed to recreate a predetermined dataset that contains feature map parameters. The algorithm was used to simulate solar system models closely resembling real life, visualized using the 3D modeling engine Blender and Unreal Engine 5.
The...
The objective of this project is to build an implementation of the Prisoner’s Dilemma game that takes advantage of quantum properties. Besides the two options we see in a classical prisoner’s dilemma, to confess and to not confess, we introduce an additional quantum option that gives both players a better...
The aviation industry is set to see another significant leap in new technology, namely electric aircraft. As of the time of this research, both 9-seat and 19-seat aircraft would be ready to be launched by air service providers under the Essential Air Service (EAS) program. While electric aircraft manufacturers are...
At her first press conference, Eleanor Roosevelt, uncertain of her role as hostess or leader, passed a box of candied grapefruit peel to the thirty-five women journalists. Nearly sixty years later, Hillary Clinton, an accomplished professional woman and lawyer, tried to mollify her critics by handing out her chocolate-chip cookie...
Winner, 2012 Frank Luther Mott-Kappa Tau Alpha Research Award
Women of the Washington Press argues that for nearly two centuries women journalists have persisted in their efforts to cover politics in the nation’s capital in spite of blatant prejudice and restrictive societal attitudes. They have been held back by the...
When Abigail Adams made her famous plea to John Adams to "remember the ladies," the role of advocacy on behalf of U.S. gender equality began its rocky and still uncompleted journey. In Women and the Press, Patricia Bradley examines the tensions that have arisen over the course of this journey...
In Spoiling the Stories, Tamar Merin presents the as yet untold story of the rise of prose by Israeli women, while further exploring and expanding the gendered models of literary influence in modern Hebrew literature. The theoretical idea upon which this book is based is that of intersexual dialogue, a...
The number of Hispanics in engineering departments at companies and universities differs from the proportion of Hispanics in the US population. Hispanics represented only 8% of the STEM (Science, Technology, Engineering and Mathematics) workforce in 2020, despite being 17% of the overall workforce. The ethnic disparity in STEM occupations contributes...
The predominant, categorical system used to classify and diagnose psychiatric disorders suffers from several critical scientific limitations, including extensive comorbidity, unreliability, and disorder heterogeneity. As such, clinical psychological scientists are increasingly moving away from this traditional, categorical system, and toward empirically-based, dimensional, and transdiagnostic alternatives such as the Hierarchical Taxonomy...
In the Maximum-a-Posteriori (MAP) Inference problem, for any given probability distribution, the goal is to find the point in the support of that distribution with the highest probability. Potts models and Determinantal Point Processes (DPPs) are probabilistic models that were introduced in the context of statistical physics several decades ago....
Over the past four decades, the rate of incarceration for women has risen significantly. Black women are disproportionately represented among incarcerated women. Formerly incarcerated women and men face similar barriers upon release from incarceration, such as obtaining stable and gainful employment, securing safe and affordable housing, and reconnecting with children...
The extracellular matrix (ECM) is a masterwork of biology, and its development was a key part of the transformation from monocellular to multicellular life. With an ECM, cells acquired the ability to cooperatively build a dynamic support network that facilitated their movement, specialization, and communication. This ECM is a hierarchical...
Metaphor is an important and pervasive phenomenon in language and cognition. The vast majority of psycholinguistic research on metaphor has focused on noun metaphors (e.g., That surgeon is a butcher; That lawyer is a shark), while relatively little has investigated the processing of verb metaphors (e.g., The car limped down...
Since Infrared radiation was discovered in 1800s, the research and applications on the infrared regime have been continually developed. The infrared detectors are the key technology in these applications and have been successfully used for medical imaging, light detection and ranging (LiDAR), free-space optical communication, target tracking and object identification...
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, causing devastating disabilities in both motor and non-motor domains following the degeneration of dopamine (DA) producing neurons of the substantia nigra pars compacta (SNc). Current treatments are highly limited in efficacy, and no established treatments currently exist to alter disease...
With the advancement of high-throughput sequencing technology, it has become much easier to extract gene expression data and to discover gene-disease associations more efficiently. Longitudinal gene expression data offer more insight into expression patterns for distinct patient groups compared to cross-sectional data. For instance, patients diagnosed with subclinical acute rejections...
This dissertation comprises three distinct essays in mechanism design and economic theory. The first chapter studies the welfare implications of consumer data ownership and voluntary disclosure. I formalize this setting within a model of mechanism design with evidence and construct the seller's optimal mechanism. Perhaps surprisingly, I find that allowing...
As our world is increasingly filled with data visualizations, having the skills to leverage data visualizations is essential for participation in society. Confident engagement with data visualizations is critical for being an educated member of society; however, research has shown that it is difficult for individuals to digest and gain...
Motivated by rhythms in the brain, we investigate the synchronization of noisy and all-to-all pulse-coupled oscillators. We consider a case where the oscillatory excursions are of varying amplitude and where only sufficiently large excursions result in the output pulses that drive the interactions between the oscillators. In the regime of...
This dissertation aims to understand the contribution of schools to reducing bullying behaviors and, in turn, to examine the benefits for students of attending a school that effectively reduces bullying. In doing so, this dissertation contributes to the literature on bullying by a) locating the school as a key environment...