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-
- Description:
- Regulatory T (Treg) cells are required to control immune responses and maintain homeostasis, but are a significant barrier to antitumor immunity. Conversely, Treg instability, characterized by loss of the master transcription factor Foxp3 and acquisition of proinflammatory properties, can promote autoimmunity and/or facilitate more effective tumor immunity. A comprehensive understanding...
- Keyword:
- Tumor, Treg, Ubiquitin, Foxp3, Usp21, and Usp22
- Subject:
- Biology, Cellular biology, and Immunology
- Creator:
- Montauti, Elena
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_846345 and http://dissertations.umi.com/northwestern:15780
-
- Description:
- NiTi shape memory alloy (SMA) has drawn a great deal of attention for its various applications in the medical field (orthodontics, cardiovascular stents technology, etc.) and in other engineering fields (aerospace, aircraft, automotive, etc.) as it shows shape memory effect, superelasticity and biocompatibility. The fatigue-related issues, however, are pronounced in...
- Subject:
- Materials Science
- Creator:
- Liu, Chuan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_794898 and http://dissertations.umi.com/northwestern:15461
-
- Description:
- Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique that can detect single molecules and simultaneously obtain structural information. When an analyte molecule binds to a nanostructured noble metal surface, the otherwise weak normal Raman signal is enhanced by as much as a factor of 108. This makes SERS the...
- Keyword:
- Surface-Enhanced Raman Spectroscopy and single molecule spectroscopy
- Subject:
- Physical chemistry and Nanoscience
- Creator:
- Wong, Nolan Log-chi
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14406 and etdadmin_upload_617842
-
- Description:
- This dissertation contains three empirical studies in economic history and labor economics. The first chapter discusses two sources of historical data on work stoppages in the United States: the Third Annual Report of the Commissioner of Labor (1888) and the Tenth Annual Report of the Commissioner of Labor (1896). It...
- Subject:
- Economic history and Economics
- Creator:
- Bittarello, Luca
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14721 and etdadmin_upload_669611
-
- Description:
- The leptonic and inclusive hadronic decay branching fractions of the W boson are studied using 35.9 $fb^{-1}$ of proton-proton collision data collected at $\sqrt{s}=13~TeV$ during the 2016 run of the CMS experiment. Events characterized by the production of pairs of W bosons from \ttbar and \tW processes are selected. Multiple...
- Keyword:
- lepton flavor universality, W boson branching fraction, and CMS
- Subject:
- Physics and Particle physics
- Creator:
- Chen, Ziheng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15758 and etdadmin_upload_845225
-
- Description:
- Recent discoveries in vitamin D research indicate that vitamin D is a necessary component to several organs and tissues that extends beyond bone formation Furthermore, recent research indicates that vitamin D deficiency is rampant across the globe. Historically, anthropological research has focused on the adaptive significance of skin color to...
- Keyword:
- Philippines, developmental biology, Vitamin D, biological anthropology & human biology, gender & sex, and epigenetics
- Subject:
- Physical anthropology, Public health, and Developmental biology
- Creator:
- Perez, Julianna
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15568 and etdadmin_upload_818816
-
- Description:
- Despite prevention and treatment, substantial risk for cardiovascular disease(CVD) remains in the population and CVD has been the leading global cause-of-death in past years.While high-density lipoprotein (HDL) markers such as HDL cholesterol (HDL-C) and HDL efflux (a cholesterol-transport-function assay) are associated with decreased risk of CVD, the mechanism of this...
- Keyword:
- Cardiovascular Disease, Apolipoproteins, Post-translational Modifications, Proteoforms, and Top-down Proteomics
- Subject:
- Chemistry
- Creator:
- dos Santos Seckler, Henrique
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/15/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_791345 and http://dissertations.umi.com/northwestern:15443
-
- Description:
- This dissertation contains three essays. In the first essay, "The Role of Connections in Congressional Lawmaking", I investigate the role of connections in congressional lawmaking by studying how legislators' deaths impact their peers' capacity to sponsor and advance bills in the U.S. House of Representatives. I focus on legislators who...
- Subject:
- Economics and Political science
- Creator:
- Garro Beraza, Haritz
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_723511 and http://dissertations.umi.com/northwestern:15026
-
- Description:
- Chapter 1 investigates asks the question how do financial frictions affect the type of human capital investments that students make in college? To study this question, I build a novel dataset covering more than 700,000 U.S. students, merging commencement records with address histories, credit bureau records, and professional resumes. I...
- Subject:
- Education finance
- Creator:
- Hampole, Menaka Vagesh
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_986815 and http://dissertations.umi.com/northwestern:16605
-
- Description:
- Early life adversity predicts greater health risk in later life across multiple outcomes, including cardiovascular disease (CVD) and all-cause mortality. While biological pathways are incompletely understood, evidence is increasingly highlighting immune function, specifically chronic inflammation, which is implicated in cardiometabolic diseases, certain cancers, and all-cause mortality. Links between early adversity...
- Subject:
- Physical anthropology
- Creator:
- Aronoff, Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_945998 and http://dissertations.umi.com/northwestern:16356
-
- Description:
- Chapter 1. Undergraduate Gender Diversity and Direction of Scientific Research (with Francesca Truffa) Can diversity lead to greater research focus on populations underrepresented in science? Diverse researchers can bring new questions and perspectives, but exposure to diversity may also inspire scientists, regardless of demographic identity, to pursue new topics. This...
- Subject:
- Labor economics
- Creator:
- Wong, Ashley
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_899059 and http://dissertations.umi.com/northwestern:16019
-
- Description:
- This work is composed of two separate projects that contribute to the field’s understanding of Neisseria gonorrhoeae genetics and physiology. First, I showed that N. gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection. We measured which strain...
- Keyword:
- Bacterial genetics, Microbiology, Neisseria gonorrhoeae, and Bacteriology
- Subject:
- Microbiology
- Creator:
- Quillin, Sarah Jane
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 04/29/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14977 and etdadmin_upload_716337
-
- Description:
- Evolutionary theory predicts that reproduction entails energetic costs that detract from somatic maintenance, accelerating biological aging. In women, such ‘costs of reproduction’ (CoR) are thought to arise predominantly during pregnancy and lactation, while in men the physiological effects of the steroid hormone testosterone (T) are believed to be a major...
- Keyword:
- Epigenetic clocks, Tradeoffs, Disposable soma theory, Costs of reproduction, Aging, and DNA methylation
- Subject:
- Genetics, Evolution & development, and Biology
- Creator:
- Ryan, Calen Patrick
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_780539 and http://dissertations.umi.com/northwestern:15395
-
- Description:
- The high-temperature oxidation/reduction behaviors of iron and its oxides are important to a variety of energy conversion and storage technologies, such as the solid-oxide iron-air battery and chemical looping combustion. The useful lifetime of iron redox materials is limited, however, by structural degradation arising from (i) sintering, accelerated by phase...
- Subject:
- Materials Science
- Creator:
- Wilke, Stephen
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15073 and etdadmin_upload_741055
-
- Description:
- Background: Cancer-related cognitive impairment (CRCI) is among the most frequently reported adverse events during and following cancer treatment. Between 17% to 75% of chemotherapy-treated cancer patients evidence long-term cognitive deficits as many as 20 years after treatment. The variability in prevalence and the mechanisms of persistent CRCI are not well...
- Keyword:
- mild cognitive impairment, ADNI, Cancer-related cognitive impairment, cancer, Alzheimer's disease, and Aging
- Subject:
- Oncology, Clinical psychology, and Aging
- Creator:
- Eastman, Jennifer Ann
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_677366 and http://dissertations.umi.com/northwestern:14756
-
- Description:
- Prions are self-perpetuating, alternative protein conformations associated with neurological diseases and normal cellular functions. Saccharomyces cerevisiae contains many endogenous prions – providing a powerful system to study prionization. Previously, the Li Lab demonstrated that Swi1, a component of the SWI/SNF chromatin-remodeling complex, can form the prion [SWI+]. A small region,...
- Keyword:
- [SWI+], yeast, protein aggregation, prions, Saccharomyces cerevisiae, and Swi1
- Subject:
- Molecular biology, Bioinformatics, and Neurosciences
- Creator:
- Goncharoff, Dustin Kenneth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_816388 and http://dissertations.umi.com/northwestern:15538
-
- Description:
- Abstract The overall purpose of this paper is to reconsider the narrative usage and function of a literary phenomenon like ‘opposition/tension/contradiction.’ Throughout my analysis of Alain-Robbe Grillet’s La jalousie, Chloé Delaume’s J’habite dans la television and Jean Genet’s Le Balcon I was focused on investigating the use of this phenomenon...
- Subject:
- French literature
- Creator:
- Costea, Mihaela-Adina
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_639270 and http://dissertations.umi.com/northwestern:14518
-
- Description:
- A greater number of strategies in one’s coping repertoire (i.e., the number of diverse strategies used across stressors or use habitually across several situations) may be beneficial and a precursor to coping flexibly across situations (Bonnano & Burton, 2013). Indeed, previous studies have demonstrated a benefit of having larger number...
- Keyword:
- coping and well-being
- Subject:
- Psychology
- Creator:
- Bastarache, Emily Diane
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_855481 and http://dissertations.umi.com/northwestern:15815
-
- Description:
- Human skin oils are significant scavengers of atmospheric oxidants in occupied indoor environments. Many techniques used to study gas-phase transformations of surface films indoors have been limited to off-line bulk analysis, although more surface-selective methodologies are emerging. Here, we present a multi-prong analytical approach to characterizing skin oil ozonolysis. Skin...
- Keyword:
- squalene, nonlinear spectroscopy, ozonolysis, indoor air, optical profilometry, and surface science
- Subject:
- Physical chemistry and Chemistry
- Creator:
- Butman, Jana Lee
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16586 and etdadmin_upload_986300
-
- Description:
- The Operating System (OS) kernel is a key component of modern computing infrastructure, yet it is prone to numerous vulnerabilities, many of which cause memory corruptions that can be exploited by attackers to perform malicious activities. While various techniques have been introduced to secure the Linux kernel, it still constantly...
- Keyword:
- Weird machine, Kernel vulnerability, Exploitation, and Exploitability
- Subject:
- Computer science
- Creator:
- Lin, Zhenpeng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1010237 and http://dissertations.umi.com/northwestern:16700
-
- Description:
- In the first two decades of the twenty-first century, we have witnessed a surge of public interest in and discussion around racial reckoning. Universities in the United States and across the globe are grappling with their historical associations with transatlantic and chattel slavery. This dissertation takes up the question of...
- Keyword:
- reconciliation, abolition, family, rhetorical analysis, redress, and Black feminism
- Subject:
- Gender studies and Rhetoric and Composition
- Creator:
- Ferrell, Ashley P
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16749 and etdadmin_upload_1013545
-
- Description:
- Metal-organic frameworks (MOFs) are porous, crystalline materials synthesized by combining metal nodes and organic linkers through self-assembly. The diverse range of building blocks available allows for extensive tunability of MOFs, enabling the optimization of these materials for various applications, such as gas storage, separations, and catalysis. This study aimed to...
- Keyword:
- Molecular modeling, Xylene Separation, Monte carlo simulation, Chemical engineering, and Metal-organic framework
- Subject:
- Chemistry and Chemical engineering
- Creator:
- Li, Zhao
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013711 and http://dissertations.umi.com/northwestern:16763
-
- Description:
- Glioblastoma (GBM) is the most common aggressive primary malignant brain tumorin adults with a median age of onset of 65 years of age. Although advanced age is often associated with worse GBM patient survival, the predominant source(s) of maladaptive aging effects remains to be established. Here we studied intra-tumoral and...
- Keyword:
- Senescence, p16INK4a, Glioblastoma, Aging, and Immunotherapy
- Subject:
- Biology and Neurosciences
- Creator:
- Bell, April Charlotte
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16795 and etdadmin_upload_1016132
-
- Description:
- Metal–Organic Frameworks (MOFs) is a class of material comprising organic linkers and inorganic, metal-ion-containing nodes, with diverse functionalities and wide-range of applications. Because of their porous nature and functional nodes and linkers, they are competent candidates for gas storage, separation, catalysis, and so on. Most MOFs, however, are intrinsically insulating,...
- Keyword:
- Metal–Organic Frameworks, Electrochemistry, and Electrocatalysis
- Subject:
- Analytical chemistry, Chemistry, and Materials Science
- Creator:
- Duan, Jiaxin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16539 and etdadmin_upload_984686
-
- Description:
- In recent years, we have seen the embryo of Industry 4.0 which has been promoting manufacturing processes towards the future with better efficiency, higher accuracy and better reliability. However, manufacturing precision has been restricted by the precision of metrology and material characterization. In other words, one can only manufacture parts...
- Keyword:
- Digital Image Correlation, Metrology, Industry 4.0, Photometric Stereo, and Deep Learning
- Subject:
- Mechanical engineering
- Creator:
- Yang, Ru
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16719 and etdadmin_upload_1012433
-
- Description:
- Stairs and curbs often present as an exhausting environmental barrier for individuals with bilateral cerebral palsy (CP) due to their lower limb motor impairments. Indeed, performance in stair-climbing in this population has a higher correlation with disruption of mobility than walking. Community members affected by CP consider impaired mobility a...
- Subject:
- Physical therapy, Biomedical engineering, and Biomechanics
- Creator:
- Goyal, Vatsala
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16701 and etdadmin_upload_1010522
-
- Description:
- Anthropologists engaging with biopolitical theory have commonly assumed that biomedicine is a tool for enacting state-based policies to manage population health. Recent insights in medical anthropology have troubled this assumption, calling into question the role of physicians as “handmaidens” of state-based health policy. I use my position as a physician-anthropologist...
- Keyword:
- anthropology of reproduction, pregnancy, opioid use disorder, illicit substance use disorders, biopolitics, and medical anthropology
- Subject:
- Cultural anthropology
- Creator:
- Premkumar, Ashish
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_965675 and http://dissertations.umi.com/northwestern:16433
-
- Description:
- The role of providing care for a loved one with Alzheimer’s disease can expose friends and family caregivers to significant stress over an extended period of time, resulting in a host of negative outcomes like increased depression and anxiety, and diminished quality of life. However, previous studies have found that...
- Keyword:
- psychological well-being, positive emotion, caregiving, online intervention, Alzheimer's disease, and eHealth
- Subject:
- Clinical psychology, Health sciences, and Psychology
- Creator:
- Kwok, Zhenting Ian
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16329 and etdadmin_upload_941336
-
- Description:
- This thesis document is comprised of three research projects. The first investigates the active vibrational modes involved in twisted intramolecular charge transfer in a Julolidine-BODIPY dyad using two-dimensional electronic spectroscopy along with DFT calculations. We identified two types of vibrations, compression and torsional motion, as playing an important role in...
- Subject:
- Organic chemistry, Physical chemistry, and Chemistry
- Creator:
- Fisher, Jeremy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16773 and etdadmin_upload_1014057
-
- Description:
- Renewable energy technology, more so than ever before, is critical to the survival of humanity. For decades, concentrated efforts into designing and developing such novel devices resulted in the innovation of solar-driven photovoltaics that were competitive with nonrenewable alternatives. This thesis explores the dynamic behavior of alternative material candidates that...
- Keyword:
- electronic, structural, perovskite, spectroscopy, two-dimensional, and nanomaterials
- Subject:
- Physics, Chemistry, and Materials Science
- Creator:
- Panuganti, Shobhana
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1010644 and http://dissertations.umi.com/northwestern:16703
-
- Description:
- The work presented in this thesis is to describe the fabrication of the nano-composites of carbonaceous materials (e.g. graphene oxide) and metal oxides (e.g. Titanium dioxide TiO2) for two specific applications in the field of public health protection: 1.) removal of micropollutants (MPs) in the aqueous environment; 2.) antimicrobial coating.The...
- Subject:
- Environmental engineering
- Creator:
- Fu, Han
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013991 and http://dissertations.umi.com/northwestern:16770
-
- Description:
- The need for complex and sophisticated materials continues to grow as society becomes more advanced. For many chemists, the design of these materials begins by looking towards model molecular systems for the identification of desirable properties and functions. As such, restricting oneself to C, H, N, O, and the other...
- Keyword:
- metal-organic frameworks, Magnetic materials, stimuli-responsive materials, weak link approach, and coordination polymers
- Subject:
- Inorganic chemistry
- Creator:
- Coleman, Benjamin
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16793 and etdadmin_upload_1015421
-
- Description:
- Each neuron in the primary motor cortex (M1) is like a musician in an orchestra, contributing to a larger harmony under the constraint of a “neural manifold”—a geometric score describing the correlated signals produced by the neural musicians that drive movement. Despite the widespread recognition of the importance of M1...
- Keyword:
- neural networks, neural manifolds, motor control, machine learning, and brain-computer interface
- Subject:
- Biomedical engineering and Neurosciences
- Creator:
- Altan, Ege
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1001502 and http://dissertations.umi.com/northwestern:16658
-
- Description:
- Interpenetrating polymer networks (IPNs) are multicomponent materials that enhance the compatibility of otherwise immiscible polymers by trapping the microstructure in a non-equilibrium state. By combining polymers with vastly different moduli, IPNs effectively disperse rigid polymers within a soft matrix, resulting in a reinforced elastomer. This approach significantly increases the modulus...
- Keyword:
- Phase Seperation, Polymer Physics, Silicone Elastomer, Interpenetrating Polymer Networks, and Single Molecule Localization Microscopy
- Subject:
- Polymer chemistry, Plastics, and Chemical engineering
- Creator:
- Heyl, Tyler
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1001901 and http://dissertations.umi.com/northwestern:16662
-
- Description:
- Large scale adoption of sustainable technologies for energy productionand storage can be greatly facilitated by scientific advances impacting efficiency, cost and availability. The study of materials is instrumental in both upgrading the performance of existing technologies and enabling the development of new ones, and ab-initio methods and machine learning represent...
- Subject:
- Materials Science and Energy
- Creator:
- Baldassarri, Bianca
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16729 and etdadmin_upload_1012768
-
- Description:
- Chronic stress is a significant risk factor for the development of numerous psychiatric disorders, including major depressive disorder (MDD). Individuals with MDD exhibit impairments in reward processing and decreased motivation to engage in previously-rewarding activities. Importantly, there is a large sex disparity in MDD diagnosis, such that it affects nearly...
- Keyword:
- corticosterone, motivation, and dopamine
- Subject:
- Neurosciences
- Creator:
- Holloway, Ashley
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16726 and etdadmin_upload_1012569
-
- Description:
- The rise in children’s media use (Rideout & Robb, 2020) and the prioritization of STEM learning (Fayer et al., 2017) has led to the development of new STEM-related apps, TV shows, and other media for young children. One topic in this area gaining popularity is computational thinking (CT). Researchers refer...
- Keyword:
- Diversity, Culture and Inclusion, Computational Thinking, Early Childhood, Educational Television, and STEM
- Subject:
- Developmental psychology, Science education, and Communication
- Creator:
- Lemley, Breniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1011152 and http://dissertations.umi.com/northwestern:16709
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- Description:
- A proliferation of new media platforms have upended the traditional roles that journalists have played in society, placing their work into content streams that are populated by creators who mimic the surface features of their work but not their methods. As a result, journalists’ practices and news media that they...
- Keyword:
- News Literacy, Pedagogy, Journalism Education, Boundary Setting, and Constructivism
- Subject:
- Journalism, Educational philosophy, and Education
- Creator:
- Spikes, Michael Antonio
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1009657 and http://dissertations.umi.com/northwestern:16690
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- Description:
- In this dissertation, we aim to develop a theoretical understanding of foundation models and reinforcement learning. We delve into a comprehensive analysis of specific aspects within these domains. The focal points of our study are as follows: • Generative Adversarial Imitation Learning (GAIL) with Neural Networks: GAIL is poised to...
- Keyword:
- Reinforcement Leanring, In-Context Learning, Imitation Leanring, and Transformer
- Subject:
- Statistics and Operations research
- Creator:
- Zhang, Yufeng
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013414 and http://dissertations.umi.com/northwestern:16740
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- Description:
- Rivers and streams play a critical role in connecting major global carbon pools – land, oceans, and atmosphere. The longitudinal flow in rivers and streams allows for the integration and transport of fluvial particulate organic carbon (POC) from various sources and its continual transformation. A continuum-oriented perspective suggests longitudinal variations...
- Keyword:
- biomarker, particulate organic carbon, storm, stream, and agricultural watershed
- Subject:
- Environmental science and Biogeochemistry
- Creator:
- Kim, Jieun
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16775 and etdadmin_upload_1014167
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- Description:
- Kaposi’ sarcoma-associated herpesvirus (KSHV) causes primary effusion lymphoma (PEL). PEL cell lines require expression of the cellular FLICE inhibitory protein (cFLIP) for survival, although KSHV encodes a viral homolog of this protein (vFLIP). Cellular and viral FLIP proteins have several functions, including, most importantly, the inhibition of pro-apoptotic caspase 8...
- Keyword:
- cFLIP, DR4, TRAIL-R1, cell death, HHV-8, and primary effusion lymphoma
- Subject:
- Microbiology and Biology
- Creator:
- Kuehnle, Neil Joseph
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16705 and etdadmin_upload_1010776
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- Description:
- The relationship between the structure and function of proteins is a fundamental problem in biology with implications for the future of biotechnology and global health. For example, changes to the structure of a coronavirus spike protein led to a global pandemic where our best defenses were vaccines that could only...
- Subject:
- Materials Science
- Creator:
- Waltmann, Curt
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16624 and etdadmin_upload_991536
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- Description:
- Scholarly inquiry has yielded a wealth of evidence in support of narrative-based strategies for persuasion, and yet support for this approach is less consistent in relation to contentious or controversial issues. To better understand why this might be the case, the first part of this dissertation reports a theoretically-guided content...
- Keyword:
- media effects, narrative, abortion, message format, narrative persuasion, and persuasion
- Subject:
- Mass communication and Communication
- Creator:
- Brooks, John Jennings
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_1013586 and http://dissertations.umi.com/northwestern:16755
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- Description:
- Prisoner reentry has become an increasingly popular topic of research in the past few decades due to the phenomenon of mass return as a result of the era of mass incarceration. While research has been done on the experiences of the returning population before mass incarceration, few contemporary researchers have...
- Keyword:
- War on Poverty, prisons, religion, and reentry
- Subject:
- History, Criminology, and Sociology
- Creator:
- Brown, Karlia Nicole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16671 and etdadmin_upload_1004192
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- Description:
- Ankle sprains are the most common musculoskeletal injury. After an ankle sprain, about 40% of individuals develop Chronic Ankle Instability (CAI), resulting in recurrent sprains, the ankle giving way, or feelings of instability. Most sprains occur due to excess inversion of the ankle. Frontal-plane ankle stiffness quantifies the ankle’s ability...
- Subject:
- Biomedical engineering and Biomechanics
- Creator:
- Villamar, Zoe Dahlia
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16668 and etdadmin_upload_1002685
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- Description:
- “National Acts: Performance, Commemoration, and the Construction of American Public Memory” explores how sites of public commemoration created during and after the American Civil War crafted conceptions of American public memory and identities through performative processes. This dissertation looks at three commemorative efforts: the Freedmen’s Memorial Monument to Abraham Lincoln,...
- Keyword:
- public memory, performance studies, American culture, and public commemoration
- Subject:
- Theater history, American studies, and Museum studies
- Creator:
- Bryer, Rebekah M
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16732 and etdadmin_upload_1012939
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- Description:
- Dental enamel is a complex bio-composite with compositional and structural features across a wide range of length scales. Defects in these features can compromise enamel’s ability to protect the tooth, resulting in adverse health outcomes. Acquired defects like tooth decay are familiar to most people and are the subject of...
- Keyword:
- Amelogenesis, Enamel, Neural networks, X-ray diffraction, Microcomputed tomography, and Mouse models
- Subject:
- Materials Science
- Creator:
- Cooley, Victoria Mae
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16769 and etdadmin_upload_1013954
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- Description:
- Many processes in nature and human-made settings rely on the unique properties of charged metal oxide:aqueous interfaces. Despite their ubiquity, these buried interfaces are challenging to study, since any analytical technique aiming to overcome the relatively small number density of interfacial versus bulk species must be highly sensitive and surface-selective....
- Keyword:
- solid aqueous interface, second harmonic generation, nonlinear optical spectroscopy, metal oxide, heterodyne detection, and hematite
- Subject:
- Physical chemistry, Geochemistry, and Chemistry
- Creator:
- Lozier, Emilie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16725 and etdadmin_upload_1012560
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- Description:
- Caves are accessible windows into the shallow subsurface, serving as transitional ecosystems between the photosynthesis-dependent surface and the deeper subsurface. Without a source of solar energy to ultimately power carbon (C) fixation (photolithoautotrophy), cave ecosystems are either reliant on surface-derived nutrients, recovering reducing power from the microbial oxidation of redox-sensitive...
- Keyword:
- caves, network analysis, microbial ecology, and biogeochemistry
- Subject:
- Microbiology, Bioinformatics, and Geobiology
- Creator:
- Selensky, Matthew James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_993827 and http://dissertations.umi.com/northwestern:16627
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- Description:
- Global dementia diagnoses are steeply increasing. While advances in neuroimaging, neuropathology, and genetics research have improved our understanding of neurodegenerative diseases causing dementia, precise antemortem diagnosis, as well as sensitive and specific biomarkers that can facilitate a differential diagnosis and aid in participant recruitment in clinical trials, remains elusive. The...
- Subject:
- Clinical psychology
- Creator:
- Stocks, Jane
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_993222 and http://dissertations.umi.com/northwestern:16626