EGFR and cMET cross-talk is involved in breast cancer (BC) progression and resistance to different targeted therapies, however little is known about the co-expression patterns of EGFR and cMET or its prognostic significance in BC. Protein levels of EGFR, cMET and their phosphorylated proteins were measured in 825 BC samples...
The mechanisms underlying the discovery of abstract rules like those found in natural language may be evolutionarily tuned to speech, according to previous research. When infants hear speech sounds, they can learn rules that govern their combination, but when they hear non-speech sounds such as sine-wave tones, they fail to...
What makes a musician? In this review, we discuss innate and experience-dependent factors that mold the musician brain in addition to presenting new data in children that indicate that some neural enhancements in musicians unfold with continued training over development. We begin by addressing effects of training on musical expertise,...
Recent studies in quantum biology suggest that quantum mechanics help us to explore quantum processes in biological system. Here, we demonstrate generation of photon pairs through spontaneous four-wave mixing process in naturally occurring fluorescent proteins. We develop a general empirical method for analyzing the relative strength of nonlinear optical interaction...
The endothelial cell (EC) lining of the pulmonary vascular system forms a semipermeable barrier between blood and the interstitium and regulates various critical biochemical functions. Collectively, it represents a prototypical biomechanical system, where the complex hierarchical architecture, from the molecular scale to the cellular and tissue level, has an intimate...
Impairments in the social use of language, or pragmatics, constitute a core characteris-tic of autism. Problems with pragmatic language have also been documented in fragile X syndrome (FXS), a monogenic condition that is the most common known genetic cause of autism. Evidence suggests that social cognitive ability, or theory of...
A randomized experiment was conducted to assess the effectiveness of three forms of e-mail appeals to prospective members of a newly formed professional group. The baseline condition consisted of an impersonal appeal; prospective members were sent a mass e-mail encouraging them to join. Participants in the personal condition received an...
Recent work using the eye movement monitoring technique has demonstrated that when people are engaged in thought they tend to disengage from the external world by blinking or fixating on an empty portion of the visual field, such as a blank wall, or out the window at the sky. This...
One of the most notable recent developments in survey research is the increased usage of online convenience samples
drawn from Amazon’s Mechanical Turk (MTurk). While scholars have noted various social and political differences (e.g.,
age, partisanship) between MTurk and population-based samples, the breadth and depth of these variations remain unclear....
After large-scale disturbances such as fire, seeding can be necessary to reestablish a plant community and prevent soil erosion. While native plants are ideal for providing ecosystem services and supporting wildlife, currently seeded natives often fail to establish in disturbed landscapes. Further, reseeding with native plants is often hindered by...
Climate change, whether referring to historic ice ages or contemporary shifts in global climate patterns, has been linked to wide-ranging and regionally variable changes in biotic communities.
Understanding the factors that drive the maintenance of polymorphisms in plant populations has long been of interest to evolutionary biology. Variation in floral traits has often been attributed to selection by pollinators, but recent evidence suggests that other biotic and abiotic agents may also contribute to floral trait differentiation. In...
Because long-chain n-alkanes (n-C21 to n-C37) are found in the epicuticular leaf waxes of all vascular plants and are stable, long-lived molecules, the study of their molecular and isotopic compositions stands to serve as a potentially powerful tool in the fields of modern chemotaxonomy and paleoecology. This study attempts to...
Trees in urban areas offer ecosystem services like carbon sequestration, storm water attenuation, reduction of energy used in buildings and wildlife habitat. Cities invest substantial funds and resources to maintain a healthy urban forest, and much research has been done to improve its resiliency and sustainability. Studies have been done...
The prairie grasses Andropogon gerardii and Sorghastrum nutans have seeds with awns that twist in response to changes in humidity. The humidity-sensitive, or hygroscopic, part of the awn twists, moving the bent, passive portion in an arc. This trait has been demonstrated to improve seedling recruitment in other grass species...
Understanding how root traits vary within and among species, and how they respond to heterogeneous environments, can provide important insight into functional plant attributes that influence plant survival in competitive environments. Selecting plant material with root traits that will support its survival in competitive environments may help improve the outcomes...
Restoration managers may select seed from a variety sources for their restoration projects. If the purchased seed is not of the local ecotype, land managers run the risk of poor establishment in the short-term and outcrossing between local and non-local ecotypes, genetic swamping, and the loss of local genetic diversity...
Due to concerns about population declines and habitat destruction, secretive marsh birds (SMBs) are of high conservation concern at state, regional, and national levels. Gaps in research on SMB habitat pose barriers to conservation and wetland restoration efforts.