Psychosocial stress is part of everyday life, and while ubiquitous, stress plays a huge role disease development and treatment. Though the stressor’s intensity, predictability, and frequency (acute vs chronic) are important determinants of disease development, interactions with one’s genetic and epigenetic make-up also play a causal role. Major Depressive Disorder...
Many species have lost their natural habitat due to anthropogenic land use change. Ecologists are increasingly looking at habitat in cities to bolster efforts to conserve biodiversity. Green roofs are examples of urban habitats that are becoming more common globally. Green roofs can provide resources to support life in an...
The Bcl-2 family is considered the guardian of the mitochondrial apoptotic pathway. While there are numerous endogenous Bcl-2 antagonists that share similar homology, structure, topology, and expression pattern, only the loss of Bim in mice is sufficient to lead to the development of a systemic autoimmunity. Even loss of both...
Of the thousands of planetary candidates discovered by the Kepler mission, roughly a third are in known multiple transiting-planet systems. High-multiplicity Kepler systems (referred to as Kepler Multis) are often tightly packed and may be on the verge of instability. Many systems of this type could have experienced past instabilities,...
Most lubricants contain a series of additives that reduce friction and wear, and protect contacting surfaces. The design of these additives must be modernized to meet the challenges involved with high operating temperatures, extreme environmental conditions, and increasingly stringent environmental regulations. This research demonstrates three novel lubricant additive strategies that...
The Pseudomonas aeruginosa type III secretion system delivers effector proteins directly into target cells, allowing the bacterium to modulate host cell functions. ExoU is the most cytotoxic of the known effector proteins and has been associated with more severe infections in humans. Previous studies have shown that ExoU is a...
Some five years ago, during the first year of my assistantship at the Music Academy in Katowice, I required students to analyse some of Penderecki's early, so-called "sonoristic" pieces. The outcome of that assignment proved unsatisfactory, however, because the students tended to describe Penderecki's pieces as chaotic assemblages of sound...
In the near future, self-driving or driverless vehicles will operate without human control, enabling passengers to use their time in new ways. This opens up avenues for designing new interactions and experiences for individuals or groups traveling in an automobile. For that scenario, automobile manufacturers propose developing bigger and better...
The promise of next-generation electronics, which combines features such as mechanical flexibility, optical transparency, and relatively low-cost, has stimulated tremendous research efforts during the past few years. As perhaps the most fundamental component of an electronic circuit, the design and optimization of the thin film transistor (TFT) is of great...