Index Catalog // Arch : Northwestern University Institutional Repository

Description:: In the field of clinical diagnostics, biosensors are used to identify genetic disorders by hybridizing a surface-bound DNA sequence with the patient’s DNA. To further improve biosensor design, two nonlinear optical techniques, sum frequency generation (SFG) and second harmonic generation (SHG), were used to probe the orientation, chirality, and surface...
Keyword:: Volume 6
Creator:: Franz M. Geiger, Laurel M. Heckman, and Faith C. Boman
Owner:: Scholarly Digital Publishing
Date Uploaded:: 07/23/2018
Date Modified:: 07/23/2018
Date Created:: 2009
Resource Type:: Article

Description:: Second harmonic generation (SHG), a nonlinear optical tool, was used to characterize DNA bound through a chemical linker to the flat surface of a hemispherical lens. Contact angle measurements were used to guarantee that the chemical linker did not hydrolyze under experimental conditions. SHG experiments followed the effects of salt...
Keyword:: 2007
Creator:: Franz M. Geiger, Faith C. Boman, and Allison G. Condie
Owner:: Scholarly Digital Publishing
Date Uploaded:: 07/18/2018
Date Modified:: 07/18/2018
Date Created:: 2007
Resource Type:: Article

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