Northwestern University

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Filtering by: Creator Jaclyn Iera Subject Chemistry

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Design and synthesis of small molecules, polyamines, and N-acylated polyamines that affect biological systems

Description:

The focus of this thesis is the design of non-natural molecules for use in biological applications. Chapter one details a strategy to use small molecules to reactivate mutated p53, an oncoprotein that is prevalent in several types of cancer, back to its wild-type function. Wild-type p53 has the ability to...

Keyword:

Organic Chemistry

Subject:

Chemistry

Creator:

Jaclyn Iera

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/03/2018

Date Modified:

10/03/2018

Date Created:

2008-06-19

Resource Type:

Dissertation