Northwestern University

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Filtering by: Creator James Robert Dolan Keyword Integrase Resource type Dissertation

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Characterizing Critical Residues for the Interaction of Human Immunodeficiency Virus Type 1 Integrase with DNA Substrates

Description:

A tetramer model for HIV-1 Integrase (IN) with DNA representing the LTR termini was previously assembled which predicted amino acid residues on the enzyme surface that interact with the LTR termini (Chen et al, 2006). A separate structural alignment of HIV-1, SIV, and ASV INs predicted which of these residues...

Keyword:

HIV, DNA, model structure, and Integrase

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

James Robert Dolan

Owner:

Scholarly Digital Publishing

Date Uploaded:

09/14/2018

Date Modified:

09/14/2018

Date Created:

2008-08-27

Resource Type:

Dissertation