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Filtering by: Creator Jonathan Forrest Anker Resource type Dissertation

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Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy

Description:

Immune checkpoint inhibitors have not been effective for immunologically “cold” tumors, such as prostate cancer, which contain scarce tumor infiltrating lymphocytes. We hypothesized that select tissue-specific and immunostimulatory bacteria can potentiate these immunotherapies. Here we show that a patient-derived prostate-specific microbe, CP1, in combination with anti-PD-1 immunotherapy, increased survival and...

Keyword:

Cancer

Subject:

Driskill Graduate Training Program in Life Sciences

Creator:

Jonathan Forrest Anker

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/22/2019

Date Modified:

04/22/2019

Date Created:

2018-01-01

Resource Type:

Dissertation