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Ultra-high dimensional variable selection with application to normative aging study: DNA methylation and metabolic syndrome

Description:

Metabolic syndrome has become a major public health challenge worldwide. The association between metabolic syndrome and DNA methylation is of great research interest. We constructed a binomial model to investigate the association between a metabolic syndrome index and DNA methylation in the Normative Aging Study. We applied the Iterative Sure...

Keyword:

elastic net, Metabolic syndrome, Bootstrap, ultra-high dimensional variable selection, methylation, and ISIS

Creator:

Joel Schwartz, Brian Joyce, Pantel S. Vokonas, Yinan Zheng, Wei Zhang, Lei Liu, Tao Gao, Lifang Hou, Grace Yoon, Weihau Guan, Zhou Zhang, Andrea A. Baccarelli, Wenxin Jiang, and Haixiang Zhang

Owner:

Chris Diaz

Publisher:

BioMed Central

Date Uploaded:

05/10/2017

Date Modified:

05/10/2017

Date Created:

2017-03-07

Resource Type:

Article

Alternate Identifier:

DOI: 10.1186/s12859-017-1568-1
Detecting Dysglycemia Using the 2015 United States Preventive Services Task Force Screening Criteria: A Cohort Analysis of Community Health Center Patients

Description:

In 2015, the United States Preventive Services Task Force (USPSTF) recommended targeted screening for prediabetes and diabetes (dysglycemia) in adults who are aged 40 to 70 y old and overweight or obese. Given increasing prevalence of dysglycemia at younger ages and lower body weight, particularly among racial/ethnic minorities, we sought...

Keyword:

dysglycemia

Creator:

Sarah S. Rittner, Joseph Feinglass, Amro Hassan, Andrew Hamilton, Matthew J. O'Brien, Nivedita Mohanty, Ji Young Lee, Ronald T. Ackermann, Jessica N. Park, Maria C. Vargas, Lei Liu, David R. Buchanan, and Mercedes R. Carnethon

Owner:

Chris Diaz

Publisher:

PLOS

Date Uploaded:

05/08/2017

Date Modified:

05/08/2017

Date Created:

2016-07-12

Resource Type:

Article

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Ultra-high dimensional variable selection with application to normative aging study: DNA methylation and metabolic syndrome

Detecting Dysglycemia Using the 2015 United States Preventive Services Task Force Screening Criteria: A Cohort Analysis of Community Health Center Patients

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