Northwestern University

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Filtering by: Creator Lisa Marie Giammona Type Work Subject Chemical and Biological Engineering

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Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

Description:

Megakaryocytic cells (Mks) are derived from hematopoietic stem cells (HSCs) and give rise to platelets. Ex vivo culture of HSCs under conditions that promote Mk differentiation has been proposed as a method for producing Mks and platelets for cell therapies. Mk maturation involves the development of polyploid cells via endomitosis,...

Keyword:

Chemical and Biological Engineering

Subject:

Chemical and Biological Engineering

Creator:

Lisa Marie Giammona

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/06/2018

Date Modified:

08/06/2018

Date Created:

2007-07-23

Resource Type:

Dissertation