Northwestern University

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Filtering by: Creator Schamber, Michael Robert Resource type Dissertation

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The Mechanism of Activation and Sensitivity-Tuning of the Calcium-Sensing Receptor

Description:

Transfer of information across membranes is fundamental to the function of all organisms and is primarily initiated by transmembrane receptors. This is an allosteric process and involves conformational coupling between ligand-binding domain and signaling domain of a receptor. This allosteric mechanism of activation is unclear for many receptors. Moreover, for...

Keyword:

GPCR, CaSR, and smFRET

Subject:

Bioinformatics, Biochemistry, and Biophysics

Creator:

Schamber, Michael Robert

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

09/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16268 and etdadmin_upload_929368