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Filtering by: Creator THERON ANDREW RUSSELL Keyword Neurosciences

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Rare Schizophrenia-Associated Kalirin Variants: Possible Mechanistic Links to Cortical Neuronal Pathology

Description:

Mounting evidence indicates that known schizophrenia susceptibility genes regulate dendritic spines supports the model that perturbations in the molecular network underlying spine plasticity are crucially involved in the pathogenesis of schizophrenia. The Rac1- and RhoA-guanine nucleotide exchange factor (GEF) kalirin is critical for spine morphogenesis on cortical pyramidal neurons, and...

Keyword:

Neurosciences

Subject:

Interdepartmental Neuroscience Program (NUIN)

Creator:

THERON ANDREW RUSSELL

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/08/2019

Date Modified:

10/08/2019

Date Created:

2018-01-01

Resource Type:

Dissertation