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Filtering by: Creator William L. Klein Creator Pascale N. Lacor

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Efficient Gene Silencing in Neural Cells by Functionalized Gold Nanoparticles

Description:

Neurons are difficult to manipulate experimentally. Most transfection reagents used for gene silencing are neurotoxic, and the postmitotic state of neurons prevents the effective use of viral vectors. This study demonstrated the delivery of antisense DNA against target genes by gold nanoparticle oligonucleotide complexes (GNOs) in primary cultures of rat...

Keyword:

Volume 7

Creator:

Pascale N. Lacor, Anil R. Wadhwani, and William L. Klein

Owner:

Scholarly Digital Publishing

Date Uploaded:

07/24/2018

Date Modified:

07/24/2018

Date Created:

2010

Resource Type:

Article