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Filtering by: Creator William Sillers Type Work Keyword Clostridium acetobutylicum Keyword metabolic engineering Subject Chemical and Biological Engineering

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METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY

Description:

To increase the butanol titers and selectivity in Clostridium acetobutylicum we replaced the promoter of the alcohol/aldehyde dehydrogenase (aad) gene with the phosphotranbutyrylase (ptb) promoter and combined this with CoAT downregulation to minimize acetone production. This led to early production of high alcohol (butanol plus ethanol) titers and overall solvent...

Keyword:

metabolic engineering and Clostridium acetobutylicum

Subject:

Chemical and Biological Engineering

Creator:

William Sillers

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/01/2018

Date Modified:

10/01/2018

Date Created:

2008-12-04

Resource Type:

Dissertation

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METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY

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METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY