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Filtering by: Creator William Sillers Keyword Clostridium acetobutylicum Keyword metabolic engineering Resource type Dissertation

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1. METABOLIC ENGINEERING OF CLOSTRIDIUM ACETOBUTYLICUM FOR ENHANCED BUTANOL PRODUCTION AND SELECTIVITY

Description:: To increase the butanol titers and selectivity in <em>Clostridium acetobutylicum</em> we replaced the promoter of the alcohol/aldehyde dehydrogenase (<em>aad</em>) gene with the phosphotranbutyrylase (<em>ptb</em>) promoter and combined this with CoAT downregulation to minimize acetone production. This led to early production of high alcohol (butanol plus ethanol) titers and overall solvent...
Keyword:: metabolic engineering and Clostridium acetobutylicum
Subject:: Chemical and Biological Engineering
Creator:: William Sillers
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/01/2018
Date Modified:: 10/01/2018
Date Created:: 2008-12-04
Resource Type:: Dissertation