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Description:: A primary limitation of non-viral gene therapy is the low level of expression achieved. One of the reasons that higher expression is not achieved is that there are many physical obstacles that prevent the DNA from reaching the nucleus to be expressed. A plasmid must cross the cell membrane, traverse...
Keyword:: Cell Biology
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Erin Elizabeth Vaughan
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/30/2018
Date Modified:: 08/30/2018
Date Created:: 2007-12-07
Resource Type:: Dissertation

Description:: Filopodia play a central role in proper cell navigation; they extend from the cell surface and scan the local environment to guide the cell to its proper destination. These dynamic events require precise mechanisms for the turnover of key molecules which determine the morphology of filopodia. As of yet, such...
Keyword:: Cell Biology
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Yvonne S Aratyn
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/30/2018
Date Modified:: 08/30/2018
Date Created:: 2007-10-08
Resource Type:: Dissertation

Description:: Embryonic stem cells have the potential to differentiate into ectodermal, mesodermal and endodermal derivatives. This property makes them a valuable source of tissue specific progenitor and differentiated cells that can be used for cell replacement therapy. The first goal of this thesis is to test if cardiogenesis from embryonic stem...
Keyword:: Cell Biology
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Achuta K Guddati
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/08/2018
Date Modified:: 10/08/2018
Date Created:: 2008-05-09
Resource Type:: Dissertation

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