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Filtering by: Type Work Keyword Cell Cycle Subject Integrated Graduate Program in the Life Sciences

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DISSECTING THE ROLE OF C53 IN REGULATION OF CELL CYCLE AND CELL DEATH

Description:

Regulation of cell cycle and cell death are critical for normal cellular proliferation, tissue homeostasis, animal development, and the pathogenesis of human diseases such as cancer. Irregularities in cell cycle and cell death may result in tumorigenesis. In this dissertation, I describe my studies of a novel gene C53, which...

Keyword:

Mitosis, Cell Cycle, G2/M checkpoint, Cell Death, and C53

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Hai Jiang

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/09/2018

Date Modified:

05/09/2018

Date Created:

2006-12-12

Resource Type:

Dissertation
Control of DNA Replication by the Cdt1/Geminin Complex

Description:

It is critical to genomic integrity that DNA is replicated completely and faithfully during each cell cycle. The essential replication factor Cdt1 is a critical protein in preventing reinitiation of replication. Overexpression of Cdt1 causes re-replication in p53 null cells and transforms NIH3T3 cells, causing them to form tumors in...

Keyword:

Xenopus, Cell Cycle, Geminin, Cdt1, and Re-Replication

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Sarah Lynn Kerns

Owner:

Scholarly Digital Publishing

Date Uploaded:

06/01/2018

Date Modified:

06/01/2018

Date Created:

2007-05-11

Resource Type:

Dissertation