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Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

Description:

Megakaryocytic cells (Mks) are derived from hematopoietic stem cells (HSCs) and give rise to platelets. Ex vivo culture of HSCs under conditions that promote Mk differentiation has been proposed as a method for producing Mks and platelets for cell therapies. Mk maturation involves the development of polyploid cells via endomitosis,...

Keyword:

Chemical and Biological Engineering

Subject:

Chemical and Biological Engineering

Creator:

Lisa Marie Giammona

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/06/2018

Date Modified:

08/06/2018

Date Created:

2007-07-23

Resource Type:

Dissertation
Development and Application of Tools for Modeling Mass Transport and Catalytic Reaction in Nanostructured Membranes

Description:

Modeling and simulation at different scales were used to study mass transport, residence times and selective oxidation in nanostructured membranes. First, analytical equations of the possible mass transport mechanisms inside the pores were used to determine that diffusion dominates over convection under the conditions of interest for selective oxidation: 700...

Keyword:

Chemical and Biological Engineering

Subject:

Chemical and Biological Engineering

Creator:

Simon E Albo

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/22/2018

Date Modified:

06/01/2018

Date Created:

2007-04-23

Resource Type:

Dissertation

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Nicotinamide Enhances Primary Human Megakaryocytic Differentiation from Hematopoietic Stem Cells: Phenotypic Characterization and Mechanism of Action

Development and Application of Tools for Modeling Mass Transport and Catalytic Reaction in Nanostructured Membranes

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