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Filtering by: Type Work Keyword Prolactin Resource type Dissertation Subject Driskill Graduate Training Program in Life Sciences

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Description:: The hormone prolactin (PRL) contributes to breast cancer pathogenesis through various signaling pathways, one of the most notable being the JAK2/signal transducer and activator of transcription 5 (STAT5) pathway. PRL-induced activation of the transcription factor STAT5 results in the upregulation of numerous genes implicated in breast cancer pathogenesis. However, the...
Keyword:: Transcription factor, HMGN, Histone H1, Chromatin, STAT5, and Prolactin
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: Suzanne Marie Schauwecker
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/18/2018
Date Modified:: 04/18/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: The polypeptide hormone prolactin (PRL) is increasingly recognized as contributing to the development and progression of human breast cancer. This is supported by epidemiologic studies that found women with high levels of serum PRL are at an increased risk for developing breast cancer. Activation of the prolactin receptor (PRLR) by...
Keyword:: Focal Adhesion, Prolactin, Breast Cancer, Cell Migration, and Phosphorylation
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: Katherine Marie Schulhaus
Owner:: Scholarly Digital Publishing
Date Uploaded:: 03/13/2018
Date Modified:: 03/13/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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