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Description:: Little is known about the transcriptional events underlying megakaryocytic (Mk) differentiation from hematopoietic stem cells. We sought to identify genes and pathways not previously associated with megakaryopoiesis and to evaluate the CHRF-288-11 (CHRF) megakaryoblastic cell line as a model system for investigating megakaryopoiesis. Using DNA microarrays, Q-RT-PCR, and protein-level assays,...
Keyword:: p53, microarray, differentiation, apoptosis, polyploidization, and megakaryocyte
Subject:: Chemical and Biological Engineering
Creator:: Peter Gebhard Fuhrken
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/06/2018
Date Modified:: 08/06/2018
Date Created:: 2007-07-12
Resource Type:: Dissertation

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