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Synaptic and spiking activity of cerebellar neurons during learning and swimming in larval zebrafish

Description:

The cerebellum contributes to movement initiation, execution, and adaptation. Primary cerebellar neurons receive synaptic inputs related to sensory stimuli and motor commands, leading to modulation of their firing. Furthermore, synaptic input differs substantially between cerebellum-dependent behaviors. I have made voltage- and current-clamp recordings from Purkinje and eurydendroid neurons in the...

Keyword:

zebrafish, cerebellum, Purkinje, sensorimotor integration, and learning

Subject:

Interdepartmental Neuroscience Program (NUIN)

Creator:

Thomas Harmon

Owner:

Scholarly Digital Publishing

Date Uploaded:

10/14/2019

Date Modified:

10/14/2019

Date Created:

2018-01-01

Resource Type:

Dissertation
Integration of Synaptic Excitation and Inhibition in the Cerebellar Nuclei

Description:

Large projection neurons of the cerebellar nuclei (CbN cells), whose activity generates movement, are inhibited by Purkinje cells and excited by mossy fibers. The high convergence, firing rates, and strength of Purkinje inputs predict powerful suppression of CbN cell spiking, raising the question of what activity patterns favor excitation over...

Keyword:

deep cerebellar nuclei, cerebellum, dynamic clamp, Purkinje cell, rate coding, and temporal coding

Subject:

Interdepartmental Neuroscience Program (NUIN)

Creator:

Yeechan Wu

Owner:

Scholarly Digital Publishing

Date Uploaded:

01/09/2019

Date Modified:

01/09/2019

Date Created:

2017-01-01

Resource Type:

Dissertation

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Synaptic and spiking activity of cerebellar neurons during learning and swimming in larval zebrafish

Integration of Synaptic Excitation and Inhibition in the Cerebellar Nuclei

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