Northwestern University

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Filtering by: Type Work Keyword transcriptional regulation Keyword gene expression Keyword higher order chromatin structure

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Exploring the Roles of cis- and trans-Factors in Modulating Higher Order Chromatin Structure and Gene Expression

Description:

Gene expression is tightly regulated at the level of transcription through cooperation between cis-regulatory elements and trans-factors that bind to the regulatory elements. Together, these factors regulate the higher order chromatin structure which establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of...

Keyword:

higher order chromatin structure, gene expression, transcriptional regulation, transcriptional regulatory networks, and cis-regulatory elements

Subject:

Driskill Graduate Training Program in Life Sciences

Creator:

Rui Yang

Owner:

Scholarly Digital Publishing

Date Uploaded:

02/19/2018

Date Modified:

02/19/2018

Date Created:

2016-01-01

Resource Type:

Dissertation