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Rational Design of Nanoparticle Morphology and Surface Charge to Specify Cellular Uptake

Description:

Due to their ability to be engineered for specific cellular targeting, nanoparticles (NPs) have emerged as promising drug delivery vessels for immunotherapeutic and vaccination treatments. However, a major unsolved obstacle for cell-specific nanoparticle delivery is non-specific circulatory clearance by the mononuclear-phagocytic system(MPS). Comprised of various phagocytic cells, the MPS removes...

Keyword:

Antigen Presenting Cells, Immunotherapy, Nanoparticle Surface Charge, Nanoparticle Morphology, Cell-Specific Nanoparticle Delivery, and PEG-bl-PPS

Subject:

Biological Sciences

Creator:

Nicholas Karabin, Yufan Yang, and Evan Scott

Owner:

Scholarly Digital Publishing

Date Uploaded:

06/13/2018

Date Modified:

06/13/2018

Date Created:

2018-05-31

Resource Type:

Poster
Effect of Group 1 CD1-restricted T cells on Atherosclerosis

Description:

Approximately 1 in 3 deaths in the US is caused by cardiovascular diseases, among them atherosclerosis. Atherosclerosis occurs through excessive cholesterol deposition (hyperlipidemia) along the inner layer of the artery called the intima, resulting in plaque formation that blocks arterial blood flow and could lead to heart attacks and strokes....

Keyword:

Atherosclerosis, LDLrko, Group 1 CD1-restricted T cells, CD1d, and HJ1-T cells

Subject:

Biological Sciences

Creator:

Shon Thomas

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/20/2018

Date Modified:

04/20/2018

Date Created:

2017-05-31

Resource Type:

Poster

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Rational Design of Nanoparticle Morphology and Surface Charge to Specify Cellular Uptake

Effect of Group 1 CD1-restricted T cells on Atherosclerosis

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