Investigating the drug response at the transcriptional level is powerful for understanding the mechanism of drug adverse effects, elucidating inter-individual drug response variability and developing personalized therapies. However, drug perturbation experiments are limited to immortal cell lines which do not reflect the true physiology and gene expression of the liver,...
The search for life beyond Earth is one of the big questions in the modern science community, and a primary motivation behind a range of NASA's ground-based and space-bourne missions. In the near future, the James Webb Space Telescope, LUVOIR, and HabEx will characterize the atmospheres of nearby Earth-like exoplanets....
Regardless of how it may seem at times, the President of the United States is not in charge of all the major decisions made by the government. The laws that we must adhere to are made, formed, and passed by Congress which is composed of the House of Representatives and...
Air pollution increases mortality risk up to 18 percent due to cardiovascular causes. Poor air quality occurs more when meteorological components prevent the dispersal of pollutants in the lower atmosphere. The atmospheric and hydrological patterns change as global warming alters the pattern of circulations seasonally. The purpose of this study...
The advent of next-generation sequencing has made it increasingly feasible to survey microbes in situ, including inside buildings where many people spend extended periods of time. Microbes in buildings, and specifically in dust, are linked to various health outcomes, and the amount of antimicrobial chemicals in dust is associated to...
The sexual network topology of individuals and their communities may affect the spread of infectious disease both within and across specific populations. To better understand this process, we collected ego-centric data on the personal sexual networks of 175 young men who have sex with men. Respondents were asked to nominate...
Approximately 1 in 3 deaths in the US is caused by cardiovascular diseases, among them atherosclerosis. Atherosclerosis occurs through excessive cholesterol deposition (hyperlipidemia) along the inner layer of the artery called the intima, resulting in plaque formation that blocks arterial blood flow and could lead to heart attacks and strokes....
The High Energy Density Sciences group at SLAC National Accelerator Laboratory studies materials in extreme conditions such as very high temperatures and pressures. We use shock waves produced by the Linac Coherent Light Source to compress polycrystalline diamond samples. Compressing these samples allows us to use x-ray diffraction to study...
A survey of adults (n = 706) found low levels of awareness of two social movements aimed at decreasing weight stigma: the Fat Acceptance Movement and Health at Every Size movement. For HAES, providing a brief story of an overweight person who endorses HAES improved perceptions of the movement.
Objectives: Poor infant health is associated with lower wellbeing later in life. Food insecurity has been associated with higher rates of some morbidities in young children. However, this relationship has not been well studied in infants younger than six months or in Kenya. Thus, we sought to determine the relationship...