Limit your search
Search Constraints
Filtering by:
Type
Work
Remove constraint Type: Work
Subject
Bioengineering
Remove constraint Subject: Bioengineering
1 - 36 of 36
Number of results to display per page
Search Results
-
- Description:
- Bacteria represent the most abundant form of life on Earth and have evolved to successfully colonize nearly every environmental niche. In doing so, bacteria predominately form multicellular communities known as biofilms, resulting in increased resilience, persistence, and emergent behaviors. Consequently, biofilms present an attractive target for engineering and synthetic biology,...
- Keyword:
- pH regulation, Bacteria, Microbial communities, and Biofilms
- Subject:
- Bioengineering and Microbiology
- Creator:
- Tran, Peter
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 08/23/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16648 and etdadmin_upload_1000000
-
- Description:
- The extracellular matrix (ECM) is a masterwork of biology, and its development was a key part of the transformation from monocellular to multicellular life. With an ECM, cells acquired the ability to cooperatively build a dynamic support network that facilitated their movement, specialization, and communication. This ECM is a hierarchical...
- Keyword:
- microfluidic, biomaterial, and supramolecular
- Subject:
- Bioengineering and Materials Science
- Creator:
- Kolberg-Edelbrock, Jack
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16480 and etdadmin_upload_979260
-
- Description:
- Tailoring the design of surfaces and interfaces with nanoscale features has the ability to significantly impact biological functions for a swath of applications including drug delivery, structure assembly, and biomedicine. For example, creating spatially defined nanoscale patterns has been known to contribute to changes in cellular architecture and mechanical properties,...
- Subject:
- Bioengineering
- Creator:
- Lin, Millicent
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 05/31/2023
- Date Created:
- 2023-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16456 and etdadmin_upload_972059
-
- Description:
- Cellular translation is responsible for the synthesis of proteins, a highly diverse class of macromolecules that form the basis of biological function. In Escherichia coli, harnessing and engineering of the biomolecular components of translation, such as ribosomes, transfer RNAs (tRNAs) and aminoacyl-tRNA synthetases, has led to both biotechnology products (i.e.,...
- Keyword:
- Genome engineering, Directed evolution, Synthetic biology, and Cell chassis development
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- Gowland, Samuel Luke Walker
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/16/2023
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16336 and etdadmin_upload_943800
-
- Description:
- Protein-based biomaterials are widely used in biomedical applications and mechanical support because of their novel structural flexibility, biocompatibility and mechanical properties. Protein-based biomaterials outperform traditional synthetic materials in various environments as traditional materials lack the diverse chemical functionalities that proteins offer. Novel bioinspired techniques such as directed evolution offer the...
- Subject:
- Bioengineering, Materials Science, and Chemical engineering
- Creator:
- Chen, Yusu
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16130 and etdadmin_upload_912201
-
- Description:
- Protein-protein interactions are ubiquitous in living systems, and mediate important cellular processes from decision making to immunity against pathogens. Furthermore, protein-protein interactions are key to many protein therapeutics, pathogen diagnostics, and numerous synthetic biology applications. As a result, there has been significant effort to develop methods to express potential protein...
- Keyword:
- Minibinder, Antibodies, Diagnostics, Protein Protein Interactions, High-Throughput Screening, and Cell-Free Protein Synthesis
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- hunt, Andrew
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_911343 and http://dissertations.umi.com/northwestern:16125
-
- Description:
- Breakthroughs in large-scale biological data collection have resulted in a wealth of -omics (genomics, metabolomics, etc.) datasets in the literature. However, the development of appropriate computational techniques for their analysis is lacking, yet crucial for fully extracting the rich information contained in these datasets. The work in this dissertation describes...
- Keyword:
- Biorecording, Data Storage, Cheminformatics, Metabolomics Annotation, Machine Learning, and TdT
- Subject:
- Bioengineering, Bioinformatics, and Biochemistry
- Creator:
- Strutz, Jonathan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_911481 and http://dissertations.umi.com/northwestern:16126
-
- Description:
- Advances in methods to sequence and manipulate DNA have enabled systems that enzymatically encode information in cellular DNA in situ. These systems, broadly categorized as molecular recorders, couple signals of interest to the expression of DNA modification enzymes, resulting in signal-dependent changes in DNA sequence. While a variety of molecular...
- Subject:
- Bioengineering
- Creator:
- Callisto, Alec
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_917054 and http://dissertations.umi.com/northwestern:16155
-
- Description:
- Three in ten people worldwide lack access to a safely managed source of drinking water, with one in ten lacking access to a drinking water service altogether. This is projected to worsen in the coming years as climate change, infrastructure degradation, and poor governance work to further increase global water...
- Keyword:
- Diagnostic, Deployment, Biosensor, Water, Synthetic Biology, and RNA
- Subject:
- Bioengineering
- Creator:
- Thavarajah, Walter
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 09/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_920589 and http://dissertations.umi.com/northwestern:16173
-
- Description:
- Ensuring adequate water quality is essential for human health and for effective allocation of resources in agriculture, energy, and manufacturing. However, the current state-of-the-art for water quality testing requires expensive equipment and technical expertise to analyze samples and takes days to obtain results from off-site labs, making it inaccessible to...
- Keyword:
- Synthetic Biology, Nucleic Acid Circuit, In Vitro Transcription, Biosensor, Transcription Factor, and RNA
- Subject:
- Bioengineering and Molecular biology
- Creator:
- Jung, Jaeyoung Kirsten
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15989 and etdadmin_upload_893092
-
- Description:
- SAMDI-MS, which stands for self-assembled monolayers (SAMs) for matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS), is a powerful tool that has enabled the development of novel high-throughput screening and experimentation methods for decades. SAMDI-MS works by immobilizing analytes to functionalized SAMs prior to MS analysis and is capable of...
- Subject:
- Bioengineering, Molecular biology, and Biochemistry
- Creator:
- Pluchinsky, Adam John
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_885633 and http://dissertations.umi.com/northwestern:15968
-
- Description:
- No two cells in a population are identical to each other. Cell populations are almost universally heterogeneous, with their heterogeneity or variability often underlying complex emergent behavior and phenotypes. Heterogeneity presents a challenge to the discovery, characterization, and control of multicellular systems. Heterogeneity exists across multiple scales, ranging from the...
- Keyword:
- Circadian Rhythms, Systems Biology, Control Theory, Dynamical Systems, and Mathematical Modeling
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- Balakrishnan, Narasimhan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_879749 and http://dissertations.umi.com/northwestern:15942
-
- Description:
- Chimeric antigen receptor (CAR) T-cell therapies marry advances in cellular engineering with personalized medicine to provide patient-specific, targeted cancer treatments. Though current CAR T-cell therapies successfully target blood cell cancers, treating solid tumors has proven to be more challenging. Solid-tumor CAR designs must overcome several challenges, including tumor microenvironment barriers...
- Keyword:
- agent-based model, CAR T-cell therapy, social justice, anti-racism diversity equity and inclusion, computational biology, and engineering education
- Subject:
- Bioengineering, Education, and Chemical engineering
- Creator:
- Prybutok, Alexis Nicole
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:16073 and etdadmin_upload_902739
-
- Description:
- Biological experiments involving the manipulation and analysis of cells have always strived towards greater precision and resolution. Recent advances in micro and nanotechnology have improved the precision of manipulation and the resolution of analysis down to a single cell, thus opening new avenues of investigation. These advances have added a...
- Keyword:
- Intracellular Delivery, Microfluidics, and Localized Electroporation
- Subject:
- Bioengineering, Mechanical engineering, and Biophysics
- Creator:
- Mukherjee, Prithvijit
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/22/2022
- Date Created:
- 2022-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15955 and etdadmin_upload_882743
-
- Description:
- Current technologies capable of establishing bioresorbable orthopedic fixation devices and stents have broad utility for biomedical applications to improve constructive tissue remodeling. Recent studies and investigations on bioresorbable conductors, semiconductors, dielectrics, and polymer substrates offer a promising opportunity to propel the existing non-degradable bioelectronic devices to the promising bioresorbable electronics,...
- Keyword:
- Soft materials, Bioresorbable electronics, Solid mechanics, Functional interfaces, Implantable electronics, and MEMS
- Subject:
- Mechanics, Bioengineering, and Mechanical engineering
- Creator:
- Yang, Quansan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Modified:
- 07/18/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_824270 and http://dissertations.umi.com/northwestern:15603
-
- Description:
- Biological therapeutics have revolutionized the way we treat cancer due to their ability to target tumors discriminately, leaving healthy cells unaffected. However, our inability to tailor the structure of biologics may hamper their optimization for efficacy. This lack of programmability contributes to factors such as immunogenic responses, inability to penetrate...
- Keyword:
- Nanotechnology, Cancer therapy, Synthetic biology, Synthetic chemistry, Protein engineering, and Protein scaffolds
- Subject:
- Bioengineering, Chemistry, and Chemical engineering
- Creator:
- Kimmel, Blaise Russel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/02/2022
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_852716 and http://dissertations.umi.com/northwestern:15804
-
- Description:
- A major distinction among different skeletal muscles in the human body is the number, size, and arrangement of its cells, referred to as a muscle’s architecture. Muscle architecture is indicative of a muscle’s ability to contract and produce force and, like muscle function, is plastic. While neuromuscular plasticity is the...
- Keyword:
- Imaging, Sarcomere, Wrist, Muscle, and In vivo
- Subject:
- Bioengineering and Biomechanics
- Creator:
- Adkins, Amy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/07/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15688 and etdadmin_upload_840250
-
- Description:
- The Escherichia coli ribosome is a molecular machine capable of sequence-defined polymerization of -amino acids into proteins, a feat unmatched by any other current synthetic catalyst. It is complex in its structure, comprised of 3 RNA parts (the 5S, 16S, and 23S ribosomal RNAs) and 54 ribosomal proteins (r-proteins). Efforts...
- Keyword:
- Synthetic Biology, RNA Design, and Ribosome Engineering
- Subject:
- Bioengineering, Bioinformatics, and Chemical engineering
- Creator:
- Kim, Do Soon
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 10/06/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_831423 and http://dissertations.umi.com/northwestern:15634
-
- Description:
- By 2030, up to half of the world’s population is projected to suffer from water insecurity: a chronic scarcity of potable water due to rapidly warming temperatures, increased agricultural demand, and pollution. The health impacts of contaminated water are profound: hundreds of thousands of global deaths each year are ascribed...
- Keyword:
- diagnostics, water quality, cell-free, and synthetic biology
- Subject:
- Bioengineering, Chemical engineering, and Public health
- Creator:
- Silverman, Adam Daniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15551 and etdadmin_upload_817796
-
- Description:
- While metabolic engineering can enable the sustainable bioproduction of new materials, efforts are often impeded by pathway bottlenecks. To mitigate the effects of toxic or reactive intermediates and resource competition resulting from heterologous pathway incorporation, bacterial microcompartments (MCPs) have recently been considered for engineered compartmentalization in bacterial host organisms. MCPs...
- Keyword:
- Tag Engineering, Metabolic Engineering, Cargo Encapsulation, Bacterial Microcompartments, and Genomic Integration
- Subject:
- Bioengineering and Chemical engineering
- Creator:
- Nichols, Taylor Marie
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 06/28/2021
- Date Created:
- 2021-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_802174 and http://dissertations.umi.com/northwestern:15500
-
- Description:
- Cell-based therapies are an exciting frontier in medicine. This field is built on a simple premise—cells can be engineered to recognize and treat various human diseases. The paradigm of cell-based therapy uses biosensors to interrogate a cell’s environment and distinguish disease from health, intracellular signaling pathways and genetic circuitry to...
- Keyword:
- Cell-based therapy, Synthetic receptors, Synthetic biology, Biosensors, Transcription factors, and Immunotherapy
- Subject:
- Bioengineering, Biology, and Medicine
- Creator:
- Donahue, Patrick Sean
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Modified:
- 05/06/2022
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15420 and etdadmin_upload_781062
-
- Description:
- Over the past fifty years, techniques for synthesizing and manipulating matter on the 1-100 nanometer scale have led to the development of nanoparticle-based approaches to both disease diagnosis and treatment. The modification of nanoparticles with biological macromolecules such as proteins and nucleic acids has led to the development of highly...
- Keyword:
- Spherical Nucleic Acid, Anthrax, Aptamer, NanoFlare, Gold Nanoparticle, and CRISPR
- Subject:
- Nanotechnology, Bioengineering, and Biology
- Creator:
- Larkin, Isaac Nathaniel
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15186 and etdadmin_upload_754966
-
- Description:
- This dissertation focuses on the development of quantitative approaches for characterizing endogenous signaling pathways and designing new pathways in mammalian cells. I demonstrate how mathematical descriptions that are formulated to explain gene expression patterns can also serve as a powerful springboard for deeper analyses into the properties and functions of...
- Keyword:
- macrophage, systems biology, receptor, computational biology, transcription factor, and synthetic biology
- Subject:
- Bioengineering, Molecular biology, and Immunology
- Creator:
- Muldoon, Joseph Jacob
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/01/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:15256 and etdadmin_upload_764084
-
- Description:
- The engineering of human reproduction is one of the defining scientific advances of the past century. Methods to specifically engineer the testis have an equally long and rich history, and have experienced significant progress over the past two decades, leading to current-day breakthroughs which are shifting the paradigms by which...
- Keyword:
- testis, model, organoid, reproduction, microenvironment, and explant
- Subject:
- Bioengineering, Biology, and Endocrinology
- Creator:
- Edmonds, Maxwell Ethan
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 01/21/2021
- Date Created:
- 2020-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_743728 and http://dissertations.umi.com/northwestern:15119
-
- Description:
- Proteins represent a critical class of biomolecules, universally employed by all living organisms to fulfill essential structural, functional, and enzymatic roles necessary to support life. In nature, these polymers are composed generally of twenty natural amino acid (AA) building blocks, which can be modified with covalent adducts known as post-translational...
- Keyword:
- post-translational modification, genome engineering, cell-free protein synthesis, synthetic biology, orthogonal translation system, and non-canonical amino acid
- Subject:
- Bioengineering, Biology, and Biochemistry
- Creator:
- Des Soye, Benjamin James
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14473 and etdadmin_upload_627384
-
- Description:
- Platelets are circulating anucleate discs derived from megakaryocytes, and play major roles in hemostasis, inflammation, thrombosis, and vascular biology. Multi-phase culture systems for inducing in vitro platelet production from mature megakaryocytes have been explored to allow progenitor expansion, megakaryocyte maturation, and promotion of platelet formation and shedding. In this thesis,...
- Keyword:
- gaussian mixture models, stem cell differentiation, machine learning, and megakaryocyte
- Subject:
- Bioengineering, Bioinformatics, and Biology
- Creator:
- WU, JIA JIE
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_640286 and http://dissertations.umi.com/northwestern:14541
-
- Description:
- End-stage renal disease, or kidney failure, can result from acute kidney injury or sustained kidney damage in the form of chronic kidney disease. As the prevalence of end-stage renal disease continues to rise, the gold-standard treatment—kidney transplantation—is increasingly restricted by the shortage of transplantable donor kidneys. Bioengineered kidney tissues may...
- Keyword:
- Hydrogels, Kidney Bioengineering, Glomerular Endothelial Cells, Regenerative Engineering, Biomaterials, and Podocytes
- Subject:
- Bioengineering and Biomedical engineering
- Creator:
- Su, Jimmy
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14793 and etdadmin_upload_684137
-
- Description:
- The work in this thesis focuses on computational methods for the identification of novel enzymatic pathways. In particular this work focuses on the utilization of the Biological Network Integrated Computational Explorer (BNICE) software suite to predict de novo enzymatic pathways for the production of commercially relevant compounds and on improvements...
- Subject:
- Bioengineering and Biochemistry
- Creator:
- Stine, Andrew Eugene
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2016-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_614431 and http://dissertations.umi.com/northwestern:14393
-
- Description:
- Currently, platelet transfusions, possessing profound clinical importance in the clotting of blood and healing of wounds, are entirely derived from human volunteer donors. This approach is limited by a 5-day shelf life, the potential risk of contamination, and differences in donor/recipient immunology. In vivo, platelets are formed when bone marrow...
- Keyword:
- Applied sciences, Biological sciences, Megakaryocyte, Cell therapies, Computational fluid dynamics, and Microfluidic bioreactor
- Subject:
- Bioengineering, Chemical engineering, and Cellular biology
- Creator:
- Martinez, Andres Felipe
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_657405 and http://dissertations.umi.com/northwestern:14571
-
- Description:
- More than half of proteins in humans are modified with carbohydrates in a process called glycosylation, yet this process remains poorly understood even though approximately 1% of the expressed human genome encodes biosynthetic machinery for glycosylation. Unlike genomics and proteomics where high throughput tools are now routinely used to generate...
- Keyword:
- SAMDI, High-throughput protein synthesis, glycosylation, self-assembled monolayers, glycosyltransferase, and Mass spectrometry
- Subject:
- Bioengineering, Analytical chemistry, and Biochemistry
- Creator:
- Techner, Jose-Marc
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14598 and etdadmin_upload_661107
-
- Description:
- Biochips and high-throughput screening methods are powerful tools for studying biological processes. The combination of peptide arrays and SAMDI mass spectrometry incorporates these tools to study a broad range of biochemical transformations, including enzyme activities, to provide valuable information on substrate recognition and guide the development of diagnostic and therapeutic...
- Keyword:
- high-throughput screening, enzyme activity, peptides, self-assembled monolayers, chemical biology, and biochips
- Subject:
- Bioengineering
- Creator:
- Wood, Sarah Elizabeth
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14669 and etdadmin_upload_662973
-
- Description:
- Recent advances in combinatorial chemistry, synthetic biology, and ‘omics’ research require high-throughput methods for performing and analyzing thousands to millions of reactions in one day. However, it is a challenge to engineer high-throughput systems that can autonomously conduct and analyze such a large number of reactions in a generalizable and...
- Keyword:
- Self-assembled monolayers, Kinetics, Spatiotemporal, SAMDI Mass Spectrometry, MALDI Imaging Mass Spectrometry, and Microfluidics
- Subject:
- Bioengineering, Chemistry, and Chemical engineering
- Creator:
- Grant, Jennifer
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2018-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14444 and etdadmin_upload_625853
-
- Description:
- Millions of years of evolution have produced fascinating biological materials and structures that are optimized to perform a wide spectrum of functions essential for the survival of organisms. These biological materials have been intensively studied in order to decipher the intricate interplay between their superior material properties and structural design...
- Subject:
- Mechanics and Bioengineering
- Creator:
- Zaheri, Alireza
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_636841 and http://dissertations.umi.com/northwestern:14505
-
- Description:
- Built from non-covalent interactions, supramolecular biomaterials are highly dynamic and tunable, and recent work has shown that they are uniquely capable of mimicking functional biological structures. In this work, supramolecular biomaterials built from self-assembling peptide amphiphiles (PA) were investigated with the goal of precisely tuning their cohesive interactions to optimize...
- Keyword:
- Bone Regeneration, Biomaterials, Self-Assembly, and Supramolecular Biomaterials
- Subject:
- Bioengineering
- Creator:
- Chen, Charlotte Hui
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- http://dissertations.umi.com/northwestern:14828 and etdadmin_upload_686118
-
- Description:
- Intestinal immunity is a critical contributor to host health. The immune system in the intestine maintains both defense against pathogens and homeostasis of intestinal tissue, which is exposed to environmental influences, including microbes and ingested foods. Proper regulation of the immune response is required to prevent damage to the host....
- Keyword:
- Bioengineering, Host-Microbiome, Regulation, Immunotherapy, and Immunity
- Subject:
- Bioengineering, Medicine, and Immunology
- Creator:
- Bostick, John
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_661070 and http://dissertations.umi.com/northwestern:14597
-
- Description:
- Knee injury causes a loss of stability in the joint and frequently leads to secondary degeneration of the cartilage in the months and years after injury, which can further impair joint function and cause pain and disability. Moreover, the secondary damage to the joint appears to be worse for females...
- Subject:
- Bioengineering
- Creator:
- Powell, Bethany
- Owner:
- Scholarly Digital Publishing
- Language:
- en
- Date Uploaded:
- 02/12/2020
- Date Created:
- 2019-01-01
- Resource Type:
- Dissertation
- Alternate Identifier:
- etdadmin_upload_636837 and http://dissertations.umi.com/northwestern:14504