Northwestern University

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Filtering by: Keyword AKT Subject Integrated Graduate Program in the Life Sciences

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Dual Regulation of Glucocorticoid-Induced Leucine Zipper (GILZ) by the Glucocorticoid Receptor and Phosphatidylinositol 3-Kinase/AKT Pathways in Multiple Myeloma

Description:

Multiple Myeloma (MM) is an incurable plasma cell malignancy occurring within the bone marrow. Glucocorticoids (GCs) are widely used in the treatment of MM patients due to potent induction of apoptosis. Though known to occur via the glucocorticoid receptor (GR), the molecular details of GC-induced apoptosis in MM cells remain...

Keyword:

Multiple Myeloma, GILZ, AKT, Glucocorticoid, and PI3-kinase

Subject:

Integrated Graduate Program in the Life Sciences

Creator:

Katharine M Davies

Owner:

Scholarly Digital Publishing

Date Uploaded:

08/01/2018

Date Modified:

08/01/2018

Date Created:

2007-06-17

Resource Type:

Dissertation