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Designing Dynamic and Modular Biomolecules and Assays to Interrogate and Control Protein Fate

Description:

Cancer has long been the second-leading cause of death in the United States and represents the leading cause of death in midlife (age 40-60). While the prognosis for many cancers has vastly improved over the last thirty years, many cancers remain elusive due to the late-onset of symptoms, the specific...

Keyword:

Antibodies, Protein Switch, Cell Patterning, Machine Learning, and Breast Cancer

Subject:

Biomedical engineering

Creator:

Sykora, Daniel Joseph

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_936187 and http://dissertations.umi.com/northwestern:16305
High-Throughput Protein-Protein Interaction Screening Using Cell-Free Protein Synthesis

Description:

Protein-protein interactions are ubiquitous in living systems, and mediate important cellular processes from decision making to immunity against pathogens. Furthermore, protein-protein interactions are key to many protein therapeutics, pathogen diagnostics, and numerous synthetic biology applications. As a result, there has been significant effort to develop methods to express potential protein...

Keyword:

Minibinder, Antibodies, Diagnostics, Protein Protein Interactions, High-Throughput Screening, and Cell-Free Protein Synthesis

Subject:

Bioengineering and Chemical engineering

Creator:

hunt, Andrew

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

09/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_911343 and http://dissertations.umi.com/northwestern:16125

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Designing Dynamic and Modular Biomolecules and Assays to Interrogate and Control Protein Fate

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