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Filtering by: Keyword Apoptosis Subject Driskill Graduate Training Program in Life Sciences

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Description:: Eosinophils are major effector cells in diseases including asthma, rhinitis, certain gastrointestinal disorders and atopic dermatitis. Current treatments include mediator antagonists and anti-inflammatory drugs that reduce allergic cell numbers and inhibit mediator release, but they are not fully effective or curative. On their surface, eosinophils selectively express Siglec-8 (sialic acid-binding...
Keyword:: Siglec-8, Eosinophils, Apoptosis, and Signaling
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: Daniela Janevska Carroll
Owner:: Scholarly Digital Publishing
Date Uploaded:: 01/23/2019
Date Modified:: 01/30/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: The Bcl-2 family is considered the guardian of the mitochondrial apoptotic pathway. While there are numerous endogenous Bcl-2 antagonists that share similar homology, structure, topology, and expression pattern, only the loss of Bim in mice is sufficient to lead to the development of a systemic autoimmunity. Even loss of both...
Keyword:: Apoptosis
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: FuNien Tsai
Owner:: Scholarly Digital Publishing
Date Uploaded:: 01/23/2019
Date Modified:: 01/23/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

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