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Development of a Generalizable Strategy for Converting Metabolite Binding Proteins into Metabolite Responsive Transcription Factors

Description:

Metabolite biosensors are powerful tools for basic biological research, medical diagnostics, and biotechnological applications. However, a generalizable strategy for developing new metabolite biosensors when an existing sensor cannot be found in nature, is a persistent challenge. Furthermore, while transcription factor biosensors have the broadest range of applications, the pool of...

Keyword:

Bioengineering, Transcription factor, Synthetic biology, Promoter engineering, Protein engineering, and Metabolic engineering

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Andrew Younger

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/18/2018

Date Modified:

04/18/2018

Date Created:

2017-01-01

Resource Type:

Dissertation