Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Intestinal immunity is a critical contributor to host health. The immune system in the intestine maintains both defense against pathogens and homeostasis of intestinal tissue, which is exposed to environmental influences, including microbes and ingested foods. Proper regulation of the immune response is required to prevent damage to the host....
Keyword:: Bioengineering, Host-Microbiome, Regulation, Immunotherapy, and Immunity
Subject:: Bioengineering, Medicine, and Immunology
Creator:: Bostick, John
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_661070 and http://dissertations.umi.com/northwestern:14597

Description:: The ability to efficiently sense and respond to molecular signals is crucial for any organism's survival. Sensitive, specific and timely, microbial sensing systems provide an excellent starting point for the engineering of single-celled organisms to detect new molecules of human interest. Towards this goal, our lab pursues the engineering of...
Keyword:: Bioengineering
Subject:: Chemical and Biological Engineering
Creator:: Adebola Adeniran
Owner:: Scholarly Digital Publishing
Date Uploaded:: 09/30/2019
Date Modified:: 09/30/2019
Date Created:: 1/1/2018
Resource Type:: Dissertation

Description:: Computational models greatly benefit metabolic engineering efforts by helping to elucidate experimental observations and predict engineering targets for improved cellular performance. Additionally, supplementing experimental efforts with computational modeling can reduce the loss of time and resources in the lab by narrowing down testing conditions. In optimal cases, computational models can...
Keyword:: Bioengineering
Subject:: Chemical and Biological Engineering
Creator:: Jennifer Lane Greene
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/15/2019
Date Modified:: 02/15/2019
Date Created:: 2017-01-01
Resource Type:: Dissertation

Description:: Metabolite biosensors are powerful tools for basic biological research, medical diagnostics, and biotechnological applications. However, a generalizable strategy for developing new metabolite biosensors when an existing sensor cannot be found in nature, is a persistent challenge. Furthermore, while transcription factor biosensors have the broadest range of applications, the pool of...
Keyword:: Bioengineering, Transcription factor, Synthetic biology, Promoter engineering, Protein engineering, and Metabolic engineering
Subject:: Interdepartmental Biological Sciences (IBiS) Graduate Program
Creator:: Andrew Younger
Owner:: Scholarly Digital Publishing
Date Uploaded:: 04/18/2018
Date Modified:: 04/18/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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