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Filtering by: Keyword Cdt1 Keyword Geminin Resource type Dissertation Subject Integrated Graduate Program in the Life Sciences

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1. Control of DNA Replication by the Cdt1/Geminin Complex

Description:: It is critical to genomic integrity that DNA is replicated completely and faithfully during each cell cycle. The essential replication factor Cdt1 is a critical protein in preventing reinitiation of replication. Overexpression of Cdt1 causes re-replication in p53 null cells and transforms NIH3T3 cells, causing them to form tumors in...
Keyword:: Xenopus, Cell Cycle, Geminin, Cdt1, and Re-Replication
Subject:: Integrated Graduate Program in the Life Sciences
Creator:: Sarah Lynn Kerns
Owner:: Scholarly Digital Publishing
Date Uploaded:: 06/01/2018
Date Modified:: 06/01/2018
Date Created:: 2007-05-11
Resource Type:: Dissertation