Northwestern University

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Filtering by: Keyword Connexin Keyword Arrhythmogenic

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Desmosomal Regulation of Gap Junction Dynamics and Cellular Contractility via Small GTPases: Implications for Cardiocutaneous Disease

Description:

Desmoplakin (DP) is a component of desmosomes, critical adhesive complexes found in cardiac intercalated discs. DP is often mutated in arrhythmogenic cardiomyopathy (AC), an inherited disorder that is a frequent cause of sudden cardiac death. The disease progression of AC is characterized by cardiomyocyte cell death and replacement of the...

Keyword:

Desmosome, Desmoplakin, Rho, Arrhythmogenic, Connexin, and Cardiocutaneous

Creator:

Chen Yuan Kam

Owner:

Scholarly Digital Publishing

Date Uploaded:

11/19/2019

Date Modified:

11/19/2019

Date Created:

2018-01-01

Resource Type:

Dissertation