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Filtering by: Keyword EM algorithm Keyword False discovery rate (FDR) Subject Statistics

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Improved Estimation of the Proportion of True Null Hypotheses with Applications to Adaptive Control of FDR and Drug Screening

Description:

Many methods have been proposed for estimating the number, $m_0$ (or the proportion, $\pi_0$), of the true null hypotheses for adaptively controlling a type I error rate (e.g., the false discovery rate or FDR) using a multiple test procedure. Most of these methods eliminate ``significantly" non-null $p$-values. Then $m_0$ is...

Keyword:

False discovery rate (FDR), Long-run FDR ($l$-FDR), Mixture model, Bias-correction, $p$-values, and EM algorithm

Subject:

Statistics

Creator:

Jiaxiao Shi

Owner:

Scholarly Digital Publishing

Date Uploaded:

05/09/2018

Date Modified:

05/09/2018

Date Created:

2006-10-10

Resource Type:

Dissertation