Northwestern University

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Filtering by: Keyword FUS Proteinopathy Keyword microRNA

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Molecular and Computational Studies of TDP-43 and FUS Proteinopathies

Description:

Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are two devastating neurodegenerative diseases that affect 100,000s of people globally. They have a severe adverse impact on society, yet there are currently no early diagnostic tools or disease-modifying therapies available. Despite their clinical heterogeneity, evidence points to these diseases being on...

Keyword:

microRNA, Compositional Data Analysis, TDP-43 Proteinopathy, FUS Proteinopathy, RNA-Seq, and Mitochondria

Subject:

Molecular biology, Bioinformatics, and Neurosciences

Creator:

McGee, Warren A

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:14675 and etdadmin_upload_663037