Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Nanocarriers are drug delivery vehicles that have at least one dimension at the nanoscale (10-9 m). Engineering the nanocarrier surface is a strategy for targeting drug delivery to specific cell types to enhance efficacy and minimize side effects. A useful analogy is to consider how the chassis of an automotive...
Keyword:: Nanotechnology, Glaucoma, Immunomodulation, Protein Adsorption, Nanocarrier Chassis, and Targeted Drug Delivery
Subject:: Pharmaceutical sciences, Materials Science, and Biomedical engineering
Creator:: Vincent, Michael Patrick
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/02/2022
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15870 and etdadmin_upload_863441

Description:: Nanoparticles are nanometer scale (1-1000 nm) structures capable of encapsulating a diverse range of cargoes. Encapsulation of a cargo can drastically alter its pharmacokinetics, cytotoxicity, and biodistribution while allowing for informed and rational design of the nanoparticle itself. Poly(ethylene glycol)-block-poly(propylene sulfide) (PEG-b-PPS) is an amphiphilic diblock co-polymer able to self-assemble...
Keyword:: Glaucoma, Latrunculin A, Nanoparticles, and Targeted Delivery
Subject:: Nanotechnology and Biomedical engineering
Creator:: Stack, Trevor
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/28/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_815566 and http://dissertations.umi.com/northwestern:15530

Description:: Glaucoma is a neurodegenerative blinding disease associated with increased intraocular pressure, which is caused by an increased resistance to the outflow of aqueous humor. Although the cause for increased resistance remains unknown, it has been associated with a decreased density of pores in the cells of the inner wall endothelium...
Keyword:: Glaucoma, Schlemm's Canal, Atomic Force Microscopy, Optical Magnetic Twisting Cytometry, Cell mechanics, and Finite Element Modeling
Subject:: Biomedical Engineering
Creator:: Amir Vahabikashi
Owner:: Scholarly Digital Publishing
Date Uploaded:: 02/14/2018
Date Modified:: 02/14/2018
Date Created:: 2016-01-01
Resource Type:: Dissertation

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