Northwestern University

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Filtering by: Keyword Glioblastoma Keyword p16INK4a

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Targeting Senescent Cells to Improve Immunotherapeutic Efficacy in Older Adults with Glioblastoma

Description:

Glioblastoma (GBM) is the most common aggressive primary malignant brain tumorin adults with a median age of onset of 65 years of age. Although advanced age is often associated with worse GBM patient survival, the predominant source(s) of maladaptive aging effects remains to be established. Here we studied intra-tumoral and...

Keyword:

Senescence, p16INK4a, Glioblastoma, Aging, and Immunotherapy

Subject:

Biology and Neurosciences

Creator:

Bell, April Charlotte

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

08/23/2023

Date Created:

2023-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16795 and etdadmin_upload_1016132