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Filtering by: Keyword Glioblastoma Subject Driskill Graduate Training Program in Life Sciences

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Description:: MAPK-interacting kinase (MNK) signaling leads to activation of cap-dependent mRNA translation through phosphorylation of the eukaryotic translation initiation factor 4E (eIF4E). In cancer cells, MNK-eIF4E signaling promotes translation of oncogenic mRNAs. In glioblastoma (GBM), the deadliest malignant brain tumor, MNK-eIF4E signaling is aberrantly activated and represents a promising therapeutic target....
Keyword:: MAPK-interacting kinase, Glioblastoma, and Glioma stem cells
Subject:: Driskill Graduate Training Program in Life Sciences
Creator:: Jonathan Brooks Bell
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/26/2018
Date Modified:: 10/26/2018
Date Created:: 2017-01-01
Resource Type:: Dissertation

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