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Defining and Altering the Natural Trajectories of Glioma: Seizures and Brainstem Infiltration

Description:

Multiple facets of the natural trajectory of glioma remain poorly understood, which results in a universally poor prognosis for patients with glioma. Many patients with glioma experience tumor-associated epilepsy (TAE) throughout their disease course, but the mechanism by which TAE occurs, who is at continued risk for TAE, and whether...

Keyword:

Glioma, Glioblastoma, Infiltration, IDH, and Seizure

Subject:

Oncology and Cellular biology

Creator:

Drumm, Michael Raymond

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

05/31/2023

Date Created:

2023-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16570 and etdadmin_upload_985850
LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement

Description:

Background: Glioblastoma (GBM) tumors are the most malignant brain cancers and are characterized as Grade IV astrocytomas by the World Health Organization. GBM tumors can be classified into three molecular subtypes known as proneural, classical, and mesenchymal. In addition, GBM tumors also have a small population of cells known as...

Keyword:

LY6K, Methylation, Glioblastoma, ERK1/2, and CAV-1

Subject:

Molecular biology, Oncology, and Neurosciences

Creator:

Sastry, Namratha G

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

01/21/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_733180 and http://dissertations.umi.com/northwestern:15049

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Defining and Altering the Natural Trajectories of Glioma: Seizures and Brainstem Infiltration

LY6K Promotes Glioblastoma Tumorigenicity via CAV-1-Mediated ERK1/2 Signaling Enhancement

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