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DNA Methylation in Repetitive Elements and Cancer

Description:

DNA methylation in repetitive elements (RE) suppresses their mobility and maintains genomic stability, and decreases in it are frequently observed in tumor and/or surrogate tissues. Averaging methylation across RE in the genome is widely used to quantify global methylation. Methylation of RE in humans is considered a surrogate for global...

Keyword:

Repetitive elements, Cancer, Machine learning, and DNA methylation

Subject:

Health Sciences Integrated PhD Program

Creator:

Yinan Zheng

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/26/2018

Date Modified:

04/26/2018

Date Created:

2017-01-01

Resource Type:

Dissertation