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Bioinformatics Analysis of Top-Down Mass Spectrometry Data

Description:

Traditional bottom-up mass spectrometry-based proteomics relies on the use of an enzyme, often trypsin, to generate small peptides (typically < 25 amino acids long). In top-down proteomics, proteins remain intact and are directly measured within the mass spectrometer. This technique, while inherently simpler than bottom-up proteomics, generates data which must...

Keyword:

ProSight Lite, Top-down, Bioinformatics, Proteomics, Mass spectrometry, and Intact protein

Creator:

Paul M Thomas, Caroline J DeHart, Ryan T Fellers, Luca Fornelli, and Neil L Kelleher

Depositor:

Joseph Brent Greer

Owner:

Proteomics Center of Excellence

Publisher:

Springer

Date Uploaded:

08/03/2017

Date Modified:

08/07/2017

Date Created:

2017-02-02

Resource Type:

Dataset

Alternate Identifier:

doi:10.21985/N2Q07P