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Investigating MTCH2 as a genetic modifier of cardiomyopathy

Description:

Genetic variation in genes regulating metabolism may be advantageous in some settings but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and source of ATP. In contrast, the failing heart favors glucose as a fuel source. A bootstrap analysis for genes with deviant...

Keyword:

Heart Failure, Glucose, Cardiomyopathy, Drosophila, Metabolism, and Mitochondria

Subject:

Molecular biology, Gender studies, and Cellular biology

Creator:

Fischer, Julie Anne

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/16/2023

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:16326 and etdadmin_upload_941216
Quantitative Analysis of Cell Fate Decisions

Description:

Organismal development depends upon countless cell decisions to adopt particular fates at the appropriate time and place. These decisions are executed by systems of biochemical reactions called regulatory networks. Elucidating the general principles underlying the structure and function of these networks is vital to understanding all developmental processes, as well...

Keyword:

Development, Quantitative Biology, Cell Decisions, Mosaic Analysis, Drosophila, and Metabolism

Subject:

Chemical engineering and Developmental biology

Creator:

Bernasek, Sebastian Michal

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_663067 and http://dissertations.umi.com/northwestern:14676

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Investigating MTCH2 as a genetic modifier of cardiomyopathy

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