Index Catalog // Arch : Northwestern University Institutional Repository

Start Over

Filtering by: Keyword Metabolism Subject Neurosciences

1 - 2 of 2

List Gallery Masonry Slideshow

Defining and Therapeutically Targeting IDH1-WT Oncogenicity in GBM

Description:

Glioblastoma multiforme (GBM) is the most prevalent primary central nervous system tumor, characterized by resistance to therapeutic intervention, inevitable recurrence, and ultimately patient death. The dismal prognosis is due in part to underlying molecular factors that promote an intratumoral cellular state heterogeneity and protect tumor cells from cell death pathways....

Keyword:

Ferroptosis, Glioblastoma, Cancer, Stemness, Metabolism, and IDH1

Subject:

Molecular biology, Medicine, and Neurosciences

Creator:

Murnan, Kevin Michael

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

06/22/2022

Date Created:

2022-01-01

Resource Type:

Dissertation

Alternate Identifier:

http://dissertations.umi.com/northwestern:15885 and etdadmin_upload_865864
Mitochondrial Complex I Function in Leigh Syndrome and Aging.

Description:

Mitochondrial complex I is the primary entry point for electrons into the mitochondrial electron transport chain that is composed of 45 individual protein subunits that are encoded in both the nuclear and mitochondrial genomes. Mitochondrial complex I sits at an important nexus in the essential bioenergetic, biosynthetic, and signaling functions...

Keyword:

NDI1, NDUFS2, NDUFS4, Mitochondria, Leigh Syndrome, and Metabolism

Subject:

Biology, Aging, and Neurosciences

Creator:

McElroy, Gregory Scott

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/01/2021

Date Created:

2020-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_746970 and http://dissertations.umi.com/northwestern:15152

LIBRARIES | ARCH

Limit your search

Type

Resource type

Creator

Keyword

Subject

Language

Defining and Therapeutically Targeting IDH1-WT Oncogenicity in GBM

Mitochondrial Complex I Function in Leigh Syndrome and Aging.

Limit your search

Search Constraints

Search Results