Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Information processing in the striatum is crucial for voluntary movement control and associative learning and in the normal condition is subject to balanced dopaminergic and cholinergic modulation. However, in Parkinson's disease (PD) striatal dopamine (DA) level falls because of degeneration of DA neurons in the substantia nigra pars compacta and...
Keyword:: Neuroscience
Subject:: Neuroscience Institute Graduate Program
Creator:: Jun Ding
Owner:: Scholarly Digital Publishing
Date Uploaded:: 05/28/2018
Date Modified:: 05/28/2018
Date Created:: 2007-05-10
Resource Type:: Dissertation

Description:: A comprehensive understanding of human memory requires both cognitive and neural descriptions of memory processes along with a conception of how memory processing drives behavioral responses and subjective experiences. Noninvasive neuroimaging techniques have greatly extended our understanding of the functional characteristics of human memory, and how neural events give rise...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Joel Lawrence Voss
Owner:: Scholarly Digital Publishing
Date Uploaded:: 06/05/2018
Date Modified:: 06/05/2018
Date Created:: 2007-05-11
Resource Type:: Dissertation

Description:: Gonadotropin releasing hormone (GnRH) neurons comprise the final pathway through which the central nervous system exerts its control over the hypothalamic-pituitary-gonadal (HPG) axis. GnRH is released in a pulsatile manner, and conveyed to the anterior pituitary gland to stimulate synthesis and secretion of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Wenyu Huang
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/06/2018
Date Modified:: 08/06/2018
Date Created:: 2007-06-21
Resource Type:: Dissertation

Description:: A comprehensive understanding of how image processing occurs in the primary visual cortex (V1) requires learning what aspects of neuronal responses are driven by strong feed-forward input from the lateral geniculate nucleus (LGN), and what aspects arise due to the densely recurrent network operating within the cortex itself. From an...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Ian Micah Finn
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/16/2018
Date Modified:: 08/16/2018
Date Created:: 2007-10-22
Resource Type:: Dissertation

Description:: The growth cone is a highly specialized motile structure with a distinctive and dynamically variable morphology. Current understanding of actin-based protrusive motility has been formulated in terms of the dendritic nucleation/array treadmilling model for lamellipodial protrusion and the convergent-elongation model for filopodial protrusion, that were based upon results obtained primarily...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Anne Katherine Mongju
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/27/2018
Date Modified:: 08/27/2018
Date Created:: 2007-07-30
Resource Type:: Dissertation

Description:: Many ion channels are localized in specific subcellular domain of the neurons, and the proper localization is critical for the function of ion channels. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels (h channels) are asymmetrically distributed in the CA1 pyramidal neurons, enriched in the distal apical dendrites. H current, generated by h...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Minyoung Shin
Owner:: Scholarly Digital Publishing
Date Uploaded:: 08/27/2018
Date Modified:: 08/27/2018
Date Created:: 2007-12-07
Resource Type:: Dissertation

Description:: Sleep deprivation (Sd) preferentially impairs predictive and adaptive behaviors that shift responses based on the appropriate context. Behavioral studies implicate the frontal lobes as particularly susceptible to Sd. Aging also impairs frontal functioning, and alters the response to Sd. The interaction between age and Sd is poorly understood, and few...
Keyword:: Sleep deprivation, Cognition, Neuroscience, Recovery Sleep, Sleep, and Aging
Subject:: Neuroscience Institute Graduate Program
Creator:: Bryce Anthony Mander
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/02/2018
Date Modified:: 10/02/2018
Date Created:: 2008-12-08
Resource Type:: Dissertation

Description:: Previous research has shown that creative insight problem-solving is distinct from systematic analytical problem-solving. Behaviorally, a positive mood has shown to facilitate insights but without knowing the processes that are fundamental to insight, the mechanisms as to how a positive mood facilitates insights have remained unspecified. Here, we investigate the...
Keyword:: Neuroscience and Biology
Subject:: Neuroscience Institute Graduate Program
Creator:: Karuna Subramaniam
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/02/2018
Date Modified:: 10/02/2018
Date Created:: 2008-12-05
Resource Type:: Dissertation

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