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The Development of Microphysiological Systems for Reproductive Biology Applications

Description:

Microfluidic technologies enable multi-tissue culture and precise control of media exchange and therefore have significant potential to create more complex in vitro models of reproductive systems, including endocrine cycles. However, microfluidic technologies have largely been applied to gamete-level culture in reproductive biology, with very little progress in organ-level culture. Herein...

Keyword:

Toxicity, Oocyte, 3D Printing, Ovary, Microfluidics, and Islet

Subject:

Obstetrics, Biology, and Biomedical engineering

Creator:

Rogers, Hunter Bradley

Owner:

Scholarly Digital Publishing

Language:

en

Date Uploaded:

02/12/2020

Date Created:

2019-01-01

Resource Type:

Dissertation

Alternate Identifier:

etdadmin_upload_661219 and http://dissertations.umi.com/northwestern:14603
Regulation of Ovarian Granulosa Cell Proliferation and Differentiation by the Notch Signaling Pathway

Description:

The follicle is the functional unit of the mammalian ovary and serves as a tightly controlled microenvironment where granulosa cells nurture the growth and maturation of the oocyte. Early events in follicular development are autonomous of the hypothalamic-pituitary-gonadal axis and are instead controlled by local factors that are used in...

Keyword:

Granulosa cells, Notch pathway, Ovary, and Follicle

Subject:

Interdepartmental Biological Sciences (IBiS) Graduate Program

Creator:

Rexxi Diptya Prasasya

Owner:

Scholarly Digital Publishing

Date Uploaded:

04/01/2019

Date Modified:

04/01/2019

Date Created:

2018-01-01

Resource Type:

Dissertation

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The Development of Microphysiological Systems for Reproductive Biology Applications

Regulation of Ovarian Granulosa Cell Proliferation and Differentiation by the Notch Signaling Pathway

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