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Filtering by: Keyword Parkinson's disease Keyword basal ganglia Resource type Dissertation

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Description:: Approximately 80-90% of individuals with Parkinson’s disease (PD) develop motor speech impairments, predominantly in the form of voice dysfunction. It is known that the motor symptoms of PD arise from degeneration of the dopamine producing neurons in the substantia nigra and dysregulation of basal ganglia motor pathways. It is also...
Keyword:: neuroimaging, dysarthria, fMRI, basal ganglia, hypophonia, and Parkinson's disease
Subject:: Neurosciences and Communication
Creator:: Manes, Jordan Leigh
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/01/2021
Date Created:: 2020-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_759611 and http://dissertations.umi.com/northwestern:15211

Description:: Parkinson's disease (PD) is a movement disorder that arises following the degeneration of dopamine-producing neurons of the substantia nigra pars compacta (SNc). Patients experience a host of limiting motor symptoms such as rigidity, tremor, and a paucity of controlled movement generation. These symptoms often correspond with a predominance of abnormally...
Keyword:: KATP channel, chemogenetics, basal ganglia, subthalamic nucleus, Parkinson's disease, and autonomous activity
Subject:: Interdepartmental Neuroscience Program (NUIN)
Creator:: Eileen McIver
Owner:: Scholarly Digital Publishing
Date Uploaded:: 10/21/2019
Date Modified:: 10/21/2019
Date Created:: 2018-01-01
Resource Type:: Dissertation

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