Index Catalog // Arch : Northwestern University Institutional Repository

Description:: Three in ten people worldwide lack access to a safely managed source of drinking water, with one in ten lacking access to a drinking water service altogether. This is projected to worsen in the coming years as climate change, infrastructure degradation, and poor governance work to further increase global water...
Keyword:: Diagnostic, Deployment, Biosensor, Water, Synthetic Biology, and RNA
Subject:: Bioengineering
Creator:: Thavarajah, Walter
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 09/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_920589 and http://dissertations.umi.com/northwestern:16173

Description:: Ensuring adequate water quality is essential for human health and for effective allocation of resources in agriculture, energy, and manufacturing. However, the current state-of-the-art for water quality testing requires expensive equipment and technical expertise to analyze samples and takes days to obtain results from off-site labs, making it inaccessible to...
Keyword:: Synthetic Biology, Nucleic Acid Circuit, In Vitro Transcription, Biosensor, Transcription Factor, and RNA
Subject:: Bioengineering and Molecular biology
Creator:: Jung, Jaeyoung Kirsten
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 06/22/2022
Date Created:: 2022-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:15989 and etdadmin_upload_893092

Description:: Nucleic acids such as DNA or RNA of various lengths and structures have a wide scope of functions as therapeutic entities compared to conventional drugs. For instance, native and modified forms of nucleic acids can be used for gene silencing, genome editing, gene replacement, immune system modulation, and theranostics. While...
Keyword:: lipids, drug delivery, DNA, RNA, and nanoparticles
Subject:: Biomedical engineering
Creator:: Sinegra, Andrew
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 10/07/2021
Date Created:: 2021-01-01
Resource Type:: Dissertation
Alternate Identifier:: etdadmin_upload_845229 and http://dissertations.umi.com/northwestern:15759

Description:: The critical importance of alternative mRNA splicing and the RNA binding proteins that orchestrate this essential layer of post-transcriptional gene regulation is increasingly recognized in gene regulatory programs. We and others have shown that alternative splicing plays a causal role during the Epithelial-Mesenchymal transition, a cell-developmental program that is hijacked...
Keyword:: splicing factor, RNA, EMT, alternative splicing, RNA binding protein, and metastasis
Subject:: Bioinformatics and Biology
Creator:: Harvey, Samuel
Owner:: Scholarly Digital Publishing
Language:: en
Date Uploaded:: 02/12/2020
Date Created:: 2019-01-01
Resource Type:: Dissertation
Alternate Identifier:: http://dissertations.umi.com/northwestern:14663 and etdadmin_upload_662828

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