Advances in biosensor engineering have enabled the design of programmable molecular systems to detect a range of pathogens, nucleic acids, and chemicals. Here, we engineer and field-test a biosensor for fluoride, a major groundwater contaminant of global concern. The sensor consists of a cell-free system containing a DNA template that...
These files include source datasets for the article "Multipartite stabilization of the C. beijerincki pfl ZTP aptamer disfavors terminator hairpin folding by gating strand invasion". RELATED ARTICLE: Strobel, E.J., Cheng, L., Berman, K.E. et al. A ligand-gated strand displacement mechanism for ZTP riboswitch transcription control. Nat Chem Biol 15, 1067–1076...
In environments ranging from natural ecosystems to living organisms, small molecule signals and nanoscale forces communicate important information regarding chemical contamination and pollution, pathogenesis, and physical stressors. As these stimuli are often well below detection limits for our own senses, we depend on biosensing technologies to monitorthem. Many biosensors operate...